PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28815595-6	2017	Escitalopram and fluvoxamine (100 nM to 1 muM) reversibly inhibited nAChR currents.	Fluvoxamine	17-28	latexin	Homo sapiens	42-45	
29155491-6	2018	The CYP3A4-selective inhibitor ketoconazole (2 muM) impaired CLZ N-oxide formation in all 14 of the livers used in inhibition studies (>=50% inhibition) while the CYP1A2-selective inhibitor fluvoxamine (10 muM) decreased norCLZ formation in nine.	Fluvoxamine	193-204	latexin	Homo sapiens	47-50	
29155491-8	2018	Similarly, fluvoxamine (10 muM) readily inhibited CLZ oxidation in seven livers with high CYP1A2-mediated 7-ethoxyresorufin O-deethylation activity (at or above the median) and three livers with lower intrinsic CYP1A2 activity.	Fluvoxamine	11-22	latexin	Homo sapiens	27-30	
21273663-3	2010	The kinetic analysis of chlorpromazine metabolism carried out in the absence or presence of antidepressants showed that fluvoxamine potently inhibited chlorpromazine 5-sulfoxidation (K(i) = 2.8 muM), mono-N-demethylation (K(i) = 1.4 muM) and di-N-demethylation (K(i) = 1.1 muM) via a competitive mechanism at therapeutic antidepressant concentrations.	Fluvoxamine	120-131	latexin	Homo sapiens	194-197	
21273663-3	2010	The kinetic analysis of chlorpromazine metabolism carried out in the absence or presence of antidepressants showed that fluvoxamine potently inhibited chlorpromazine 5-sulfoxidation (K(i) = 2.8 muM), mono-N-demethylation (K(i) = 1.4 muM) and di-N-demethylation (K(i) = 1.1 muM) via a competitive mechanism at therapeutic antidepressant concentrations.	Fluvoxamine	120-131	latexin	Homo sapiens	233-236	
21273663-3	2010	The kinetic analysis of chlorpromazine metabolism carried out in the absence or presence of antidepressants showed that fluvoxamine potently inhibited chlorpromazine 5-sulfoxidation (K(i) = 2.8 muM), mono-N-demethylation (K(i) = 1.4 muM) and di-N-demethylation (K(i) = 1.1 muM) via a competitive mechanism at therapeutic antidepressant concentrations.	Fluvoxamine	120-131	latexin	Homo sapiens	233-236