PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7505123-4	1993	Particulate beta-glucan induced IL-1Ra production from human peripheral blood mononuclear cells (PBMC) but did not stimulate IL-1 beta synthesis or gene expression in these same cells.	beta-Glucans	12-23	interleukin 1 receptor antagonist	Homo sapiens	32-38	
7505123-6	1993	However, when preincubated with PBMC, monomeric beta-glucan significantly (P < .01) reduced particulate beta-glucan induction of IL-1Ra by 40%, suggesting that crosslinking of beta-glucan receptors is required for induction of IL-1Ra.	beta-Glucans	48-59	interleukin 1 receptor antagonist	Homo sapiens	132-138	
7505123-6	1993	However, when preincubated with PBMC, monomeric beta-glucan significantly (P < .01) reduced particulate beta-glucan induction of IL-1Ra by 40%, suggesting that crosslinking of beta-glucan receptors is required for induction of IL-1Ra.	beta-Glucans	48-59	interleukin 1 receptor antagonist	Homo sapiens	230-236	
7505123-6	1993	However, when preincubated with PBMC, monomeric beta-glucan significantly (P < .01) reduced particulate beta-glucan induction of IL-1Ra by 40%, suggesting that crosslinking of beta-glucan receptors is required for induction of IL-1Ra.	beta-Glucans	107-118	interleukin 1 receptor antagonist	Homo sapiens	132-138	
7505123-7	1993	In support of this, monomeric beta-glucan immobilized on plastic surfaces stimulated IL-1Ra production.	beta-Glucans	30-41	interleukin 1 receptor antagonist	Homo sapiens	85-91	
7505123-8	1993	Vitamin D3, which increases the functional capacity of beta-glucan receptors, increased IL-1Ra production induced by particulate beta-glucan, whereas dexamethasone suppressed IL-1Ra synthesis.	beta-Glucans	55-66	interleukin 1 receptor antagonist	Homo sapiens	88-94	
25461401-10	2015	Interestingly, the IL-1Ra synthesis induced by beta-glucan was blocked by inhibitors of the Akt/PI3K pathway.	beta-Glucans	47-58	interleukin 1 receptor antagonist	Homo sapiens	19-25	
25461401-5	2015	RESULTS: C. albicans induced a strong IL-1Ra response, and this induction was primarily induced by the cell-wall component beta-glucan.	beta-Glucans	123-134	interleukin 1 receptor antagonist	Homo sapiens	38-44	
25461401-11	2015	CONCLUSIONS: beta-glucan of C. albicans induces a strong IL-1Ra response, which is independent of the beta-glucan receptors dectin-1 and CR3.	beta-Glucans	13-24	interleukin 1 receptor antagonist	Homo sapiens	57-63