PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21636079-5 2011 In this study, we found that particulate yeast-derived beta-glucans could induce the maturation of murine dendritic cell line D2SC/1 cells and increase the expression of mGITRL on D2SC/1 cells via Dectin-1/Syk pathway in a dose dependent manner. beta-Glucans 55-67 spleen tyrosine kinase Mus musculus 206-209 29202301-5 2018 Furthermore, SYK inhibition markedly decreased beta-glucan-induced IL-1beta expression, suggesting that SYK is indispensable for NLRP3 inflammasome activation. beta-Glucans 47-58 spleen tyrosine kinase Mus musculus 13-16 29202301-5 2018 Furthermore, SYK inhibition markedly decreased beta-glucan-induced IL-1beta expression, suggesting that SYK is indispensable for NLRP3 inflammasome activation. beta-Glucans 47-58 spleen tyrosine kinase Mus musculus 104-107 22744837-0 2012 Structure of a beta-glucan from Grifola frondosa and its antitumor effect by activating Dectin-1/Syk/NF-kappaB signaling. beta-Glucans 15-26 spleen tyrosine kinase Mus musculus 97-100 18818389-7 2008 The dectin-1/Syk pathway is thus able to couple innate immune recognition of beta-glucans to all branches of the adaptive immune system, including CD4(+) T-helper cells, B cells, and CD8(+) cytotoxic T cells. beta-Glucans 77-89 spleen tyrosine kinase Mus musculus 13-16 25277753-7 2015 These findings were substantiated by the evidence that neutrophils from mice with the conditional deletion of Syk were defective in formation of NETs in response to beta-glucan. beta-Glucans 165-176 spleen tyrosine kinase Mus musculus 110-113