PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32911914-2 2020 Reactive oxygen species, high concentrations of adenosine triphosphate and uric acid activate the pyroptosis system, which then cleaves the pore formation mechanism of gasdermin-D, leading to the death of liver cells, accompanied by the release of interleukin-1beta, interleukin-18, and other inflammatory factors. Uric Acid 75-84 gasdermin D Homo sapiens 168-179 32650532-4 2020 Although the mechanism is very complex and needs further explanation, it appears that high levels of cholesterol, urate, and glucose activates NLRP3 inflammasome, which produces IL-1beta, IL-18, and gasdermin D. Uric Acid 114-119 gasdermin D Homo sapiens 199-210