PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21288167-2 2011 Fructosamine 3-kinase (FN3K), initially identified in erythrocytes, appears to be responsible for the removal of fructosamine from proteins, suggesting a protective role in nonenzymatic glycation. Fructosamine 113-125 fructosamine 3 kinase Homo sapiens 0-21 20967558-2 2012 Fructosamine-3-kinase (FN3K), an enzyme found in mammals and birds, phosphorylates fructosamines on the third carbon of their sugar moiety, making them unstable and causing them to detach from proteins. Fructosamine 83-96 fructosamine 3 kinase Homo sapiens 0-21 20967558-2 2012 Fructosamine-3-kinase (FN3K), an enzyme found in mammals and birds, phosphorylates fructosamines on the third carbon of their sugar moiety, making them unstable and causing them to detach from proteins. Fructosamine 83-96 fructosamine 3 kinase Homo sapiens 23-27 21288167-2 2011 Fructosamine 3-kinase (FN3K), initially identified in erythrocytes, appears to be responsible for the removal of fructosamine from proteins, suggesting a protective role in nonenzymatic glycation. Fructosamine 113-125 fructosamine 3 kinase Homo sapiens 23-27 16920277-3 2007 Because of these considerations, we have proposed that the intrinsic toxicity of glucose and other sugars is counteracted in vivo by active deglycation mechanisms including transglycation of Schiff"s bases and FN3K-dependent breakdown of fructosamines. Fructosamine 238-251 fructosamine 3 kinase Homo sapiens 210-214 17686456-1 2007 Fructosamine-3-kinase (FN3K) phosphorylates fructosamines to fructosamine-3-phosphates. Fructosamine 44-57 fructosamine 3 kinase Homo sapiens 0-21 17686456-1 2007 Fructosamine-3-kinase (FN3K) phosphorylates fructosamines to fructosamine-3-phosphates. Fructosamine 44-57 fructosamine 3 kinase Homo sapiens 23-27 17681011-1 2007 The purpose of this work was to identify the function of bacterial homologues of fructosamine 3-kinase (FN3K), a mammalian enzyme responsible for the removal of fructosamines from proteins. Fructosamine 161-174 fructosamine 3 kinase Homo sapiens 81-102 17681011-1 2007 The purpose of this work was to identify the function of bacterial homologues of fructosamine 3-kinase (FN3K), a mammalian enzyme responsible for the removal of fructosamines from proteins. Fructosamine 161-174 fructosamine 3 kinase Homo sapiens 104-108 19834870-3 2010 Fructosamine-3-kinase (FN3K) is an intracellular enzyme that phosphorylates fructosamines resulting in fructosamine-3-phosphate, which subsequently decomposes to inorganic phosphate, 3-deoxyglucasone and the unmodified amine. Fructosamine 76-89 fructosamine 3 kinase Homo sapiens 0-21 19834870-3 2010 Fructosamine-3-kinase (FN3K) is an intracellular enzyme that phosphorylates fructosamines resulting in fructosamine-3-phosphate, which subsequently decomposes to inorganic phosphate, 3-deoxyglucasone and the unmodified amine. Fructosamine 76-89 fructosamine 3 kinase Homo sapiens 23-27 17072594-1 2006 Fructosamine-3-kinase (FN3K) mediates the regeneration of lysine from fructosamines formed on proteins as a result of the "early" Maillard reaction. Fructosamine 70-83 fructosamine 3 kinase Homo sapiens 0-21 18334852-2 2007 Instead, recent identification of fructosamine 3 kinase (FN3K) has unveiled that fructosamines can be physiologically repaired, so that the FN3K enzyme could be considered a new form of protein repair. Fructosamine 81-94 fructosamine 3 kinase Homo sapiens 34-55 18334852-2 2007 Instead, recent identification of fructosamine 3 kinase (FN3K) has unveiled that fructosamines can be physiologically repaired, so that the FN3K enzyme could be considered a new form of protein repair. Fructosamine 81-94 fructosamine 3 kinase Homo sapiens 57-61 18334852-2 2007 Instead, recent identification of fructosamine 3 kinase (FN3K) has unveiled that fructosamines can be physiologically repaired, so that the FN3K enzyme could be considered a new form of protein repair. Fructosamine 81-94 fructosamine 3 kinase Homo sapiens 140-144 17072594-1 2006 Fructosamine-3-kinase (FN3K) mediates the regeneration of lysine from fructosamines formed on proteins as a result of the "early" Maillard reaction. Fructosamine 70-83 fructosamine 3 kinase Homo sapiens 23-27 17072594-2 2006 As fructosamines and advanced glycation endproducts derived therefrom are supposed to play an adverse role in the development of diabetic complications, FN3K is discussed as a protein-repairing enzyme. Fructosamine 3-16 fructosamine 3 kinase Homo sapiens 153-157 17072594-4 2006 The assay is based on the FN3K-dependent conversion of the synthetic UV-active fructosamine Nalpha-hippuryl-Nepsilon-(1-deoxy-D-fructosyl)lysine (BzGFruK) to Nalpha-hippuryl-Nepsilon-(phosphofructosyl)lysine (BzGpFruK). Fructosamine 79-91 fructosamine 3 kinase Homo sapiens 26-30 16523184-1 2006 BACKGROUND: Part of the fructosamines that are bound to intracellular proteins are repaired by fructosamine 3-kinase (FN3K). Fructosamine 24-37 fructosamine 3 kinase Homo sapiens 95-116 16670083-1 2006 Fructosamine-3-kinase (FN3K) is a recently described protein-repair enzyme responsible for the removal of fructosamines, which are the products of a spontaneous reaction of glucose with amines. Fructosamine 106-119 fructosamine 3 kinase Homo sapiens 0-21 16670083-1 2006 Fructosamine-3-kinase (FN3K) is a recently described protein-repair enzyme responsible for the removal of fructosamines, which are the products of a spontaneous reaction of glucose with amines. Fructosamine 106-119 fructosamine 3 kinase Homo sapiens 23-27 16523184-1 2006 BACKGROUND: Part of the fructosamines that are bound to intracellular proteins are repaired by fructosamine 3-kinase (FN3K). Fructosamine 24-37 fructosamine 3 kinase Homo sapiens 118-122 15922110-0 2005 Intrinsic toxicity of glucose, due to non-enzymatic glycation, is controlled in-vivo by deglycation systems including: FN3K-mediated deglycation of fructosamines and transglycation of aldosamines. Fructosamine 148-161 fructosamine 3 kinase Homo sapiens 119-123 15705060-1 2005 FN3K (fructosamine 3-kinase) is a mammalian enzyme that catalyses the phosphorylation of fructosamines, which thereby becomes unstable and detaches from proteins. Fructosamine 89-102 fructosamine 3 kinase Homo sapiens 0-4 15705060-1 2005 FN3K (fructosamine 3-kinase) is a mammalian enzyme that catalyses the phosphorylation of fructosamines, which thereby becomes unstable and detaches from proteins. Fructosamine 89-102 fructosamine 3 kinase Homo sapiens 6-27 15366734-2 2004 Quite to the contrary, a mammalian enzyme, fructosamine 3-kinase, has recently been identified, which phosphorylates fructosamines on their third carbon, making them unstable and leading to their shedding from proteins. Fructosamine 117-130 fructosamine 3 kinase Homo sapiens 43-64 15102834-0 2004 Identification of fructosamine residues deglycated by fructosamine-3-kinase in human hemoglobin. Fructosamine 18-30 fructosamine 3 kinase Homo sapiens 54-75 15102834-1 2004 Fructosamine-3-kinase (FN3K) phosphorylates fructosamine residues, leading to their destabilization and their shedding from protein. Fructosamine 44-56 fructosamine 3 kinase Homo sapiens 0-21 15102834-1 2004 Fructosamine-3-kinase (FN3K) phosphorylates fructosamine residues, leading to their destabilization and their shedding from protein. Fructosamine 44-56 fructosamine 3 kinase Homo sapiens 23-27 15102834-3 2004 The aim of this work was to identify the fructosamine residues on hemoglobin that are removed as a result of the action of FN3K in intact erythrocytes. Fructosamine 41-53 fructosamine 3 kinase Homo sapiens 123-127 15137908-1 2004 Fructosamine 3-kinase (FN3K), an enzyme initially identified in erythrocytes, catalyses the phosphorylation of fructosamines on their third carbon, leading to their destabilization and their removal from protein. Fructosamine 111-124 fructosamine 3 kinase Homo sapiens 0-21 15137908-1 2004 Fructosamine 3-kinase (FN3K), an enzyme initially identified in erythrocytes, catalyses the phosphorylation of fructosamines on their third carbon, leading to their destabilization and their removal from protein. Fructosamine 111-124 fructosamine 3 kinase Homo sapiens 23-27 14633848-0 2003 A mammalian protein homologous to fructosamine-3-kinase is a ketosamine-3-kinase acting on psicosamines and ribulosamines but not on fructosamines. Fructosamine 133-146 fructosamine 3 kinase Homo sapiens 34-55 14641062-4 2003 Fructosamine 3-kinase phosphorylates with high affinity both low-molecular-mass and protein-bound fructosamines on the third carbon of their deoxyfructose moiety, leading to the formation of fructosamine 3-phosphates. Fructosamine 98-111 fructosamine 3 kinase Homo sapiens 0-21 14633848-1 2003 Fructosamine-3-kinase (FN3K) is an enzyme that appears to be responsible for the removal of fructosamines from proteins. Fructosamine 92-105 fructosamine 3 kinase Homo sapiens 0-21 14633848-1 2003 Fructosamine-3-kinase (FN3K) is an enzyme that appears to be responsible for the removal of fructosamines from proteins. Fructosamine 92-105 fructosamine 3 kinase Homo sapiens 23-27 14633848-11 2003 This role is shared by fructosamine-3-kinase (ketosamine-3-kinase 1), which has, in addition, the unique capacity to phosphorylate fructosamines. Fructosamine 131-144 fructosamine 3 kinase Homo sapiens 23-44 11975663-1 2002 Fructosamine 3-kinase, which phosphorylates low-molecular-mass and protein-bound fructosamines on the third carbon of their deoxyfructose moiety, is quite active in erythrocytes, and was proposed to initiate a process removing fructosamine residues from proteins. Fructosamine 81-94 fructosamine 3 kinase Homo sapiens 0-21 11975663-1 2002 Fructosamine 3-kinase, which phosphorylates low-molecular-mass and protein-bound fructosamines on the third carbon of their deoxyfructose moiety, is quite active in erythrocytes, and was proposed to initiate a process removing fructosamine residues from proteins. Fructosamine 81-93 fructosamine 3 kinase Homo sapiens 0-21 27394048-4 2017 The dialyzed solution (containing +-1000 micromol/L fructosamine) was used as an FN3K substrate. Fructosamine 52-64 fructosamine 3 kinase Homo sapiens 81-85 27394048-7 2017 The decrease in fructosamine concentration over time is a measure for the FN3K activity (1 U corresponding to 1 micromol/min). Fructosamine 16-28 fructosamine 3 kinase Homo sapiens 74-78 26850632-7 2016 An in vitro removal of fructosamine of the valve was initiated using ATP-dependent fructosamine 3-kinase (FN3K). Fructosamine 23-35 fructosamine 3 kinase Homo sapiens 83-104 26850632-7 2016 An in vitro removal of fructosamine of the valve was initiated using ATP-dependent fructosamine 3-kinase (FN3K). Fructosamine 23-35 fructosamine 3 kinase Homo sapiens 106-110 26850632-11 2016 In the in vitro deglycation study, a significant lower aortic valve fructosamine concentration was detected after treatment with FN3K. Fructosamine 68-80 fructosamine 3 kinase Homo sapiens 129-133 26352355-5 2015 FN3K phosphorylates fructosamines on the third carbon of their sugar moiety, making them unstable and causing them to detach from proteins, suggesting a protective role of this enzyme. Fructosamine 20-33 fructosamine 3 kinase Homo sapiens 0-4