PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35212533-2 2022 4-(Diethylamino)benzaldehyde (DEAB) has been extensively reported as a pan-inhibitor of ALDH isoforms, and here, we report on the synthesis, ALDH isoform selectivity, and cellular potencies in prostate cancer cells of 40 DEAB analogues; three analogues (14, 15, and 16) showed potent inhibitory activity against ALDH1A3, and two analogues (18 and 19) showed potent inhibitory activity against ALDH3A1. 4-(diethylamino)benzaldehyde 0-28 aldehyde dehydrogenase 1 family member A3 Homo sapiens 312-319 35212533-2 2022 4-(Diethylamino)benzaldehyde (DEAB) has been extensively reported as a pan-inhibitor of ALDH isoforms, and here, we report on the synthesis, ALDH isoform selectivity, and cellular potencies in prostate cancer cells of 40 DEAB analogues; three analogues (14, 15, and 16) showed potent inhibitory activity against ALDH1A3, and two analogues (18 and 19) showed potent inhibitory activity against ALDH3A1. 4-(diethylamino)benzaldehyde 30-34 aldehyde dehydrogenase 1 family member A3 Homo sapiens 312-319