PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32126132-9	2020	This salt sensitivity would be mediated by an increase in renomedullary expression and activity of AQP2 and alpha-ENaC as a consequence of increased AC6 expression and cAMP production and/or a decreased ET-1 production in the renal medulla.	Salts	5-9	aquaporin 2	Rattus norvegicus	99-103	
22587908-12	2012	SIGNIFICANCE: These results show that increased intrarenal Ang II in rats fed with a high-salt diet downregulates renal AQP-1 and AQP-2 expressions.	Salts	90-94	aquaporin 2	Rattus norvegicus	130-135	
21451595-12	2011	The downregulation of AQP1 and AQP2 and the upregulation of AQP4 may be relevant for the onset and maintenance of salt-sensitive hypertension.	Salts	114-118	aquaporin 2	Rattus norvegicus	31-35	
18177483-13	2008	We conclude that noradrenaline-induced increases in the expression of NHE-3, NBC-1, BSC-1 and aquaporin-2 are likely to play an important role in the regulation of salt and water transport by noradrenaline in the kidney and may explain, at least in part, the altered renal sodium and water handling associated with overactivation of the sympathetic system.	Salts	164-168	aquaporin 2	Rattus norvegicus	94-105	
12176047-0	2002	Aquaporin-2 transcript is differentially regulated by dietary salt in Sprague-Dawley and Dahl SS/Jr rats.	Salts	62-66	aquaporin 2	Rattus norvegicus	0-11	
12176047-2	2002	AQP-2 transcript has been identified by transcriptional profiling of rat kidneys as being regulated by dietary salt.	Salts	111-115	aquaporin 2	Rattus norvegicus	0-5	
12176047-6	2002	The present results provide evidence that: (1)AQP-2 plays a role in salt adaptation and (2) regulation of aquaporin transcript expression by salt is altered in the Dahl SS/Jr rat.	Salts	68-72	aquaporin 2	Rattus norvegicus	46-51	
10937843-0	2000	Increased expression and shuttling of aquaporin-2 water channels in the kidney in DOCA-salt hypertensive rats.	Salts	87-91	aquaporin 2	Rattus norvegicus	38-49	
10937843-1	2000	An altered role of AQP2 water channels in DOCA-salt hypertension was investigated.	Salts	47-51	aquaporin 2	Rattus norvegicus	19-23	
10751213-9	2000	The differences between rabbits and rats in the distribution patterns of ENaC and AQP2 may explain functional differences in renal salt and water handling between these species.	Salts	131-135	aquaporin 2	Rattus norvegicus	82-86