PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19602844-6	2009	TMT-induced activation of caspase-3 and calpain was also enhanced by adrenalectomy.	trimethyltin	0-3	caspase 3	Mus musculus	26-35	
25895139-11	2016	At the same time, TMT-induced inhibition of phosphoinositol 3-kinase (PI3K)/Akt signaling was evident, thereby decreasing phospho-Bad, expression of Bcl-xL and Bcl-2, and the interaction between phospho-Bad and 14-3-3 protein, and increasing Bax expression and caspase-3 cleavage were observed.	trimethyltin	18-21	caspase 3	Mus musculus	261-270	
21290413-0	2011	Trimethyltin initially activates the caspase 8/caspase 3 pathway for damaging the primary cultured cortical neurons derived from embryonic mice.	trimethyltin	0-12	caspase 3	Mus musculus	47-56	
21290413-10	2011	Taken together, our data are the first demonstration that TMT toxicity is initially caused by activation of the caspase 8/caspase 3 pathway for nuclear translocation of DNases in cortical neurons in primary culture.	trimethyltin	58-61	caspase 3	Mus musculus	122-131	
12009767-0	2002	Cyclooxygenase-2 and caspase 3 expression in trimethyltin-induced apoptosis in the mouse hippocampus.	trimethyltin	45-57	caspase 3	Mus musculus	21-30