PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23916291-0 2013 A subset of malignant phyllodes tumors harbors alterations in the Rb/p16 pathway. phyllodes 22-31 cyclin dependent kinase inhibitor 2A Homo sapiens 69-72 23916291-2 2013 Here, we systematically study p16 and Rb expression in 34 phyllodes tumors in relation to proliferation. phyllodes 58-67 cyclin dependent kinase inhibitor 2A Homo sapiens 30-33 23916291-8 2013 Twenty-nine percent (4/14) malignant phyllodes showed diffuse strong p16 labeling with Rb loss in malignant cells (diffuse p16+/Rb-), whereas 21% (3/14) malignant phyllodes showed the reverse pattern of p16 loss with diffuse strong Rb (p16-/diffuse Rb+). phyllodes 37-46 cyclin dependent kinase inhibitor 2A Homo sapiens 69-72 23916291-8 2013 Twenty-nine percent (4/14) malignant phyllodes showed diffuse strong p16 labeling with Rb loss in malignant cells (diffuse p16+/Rb-), whereas 21% (3/14) malignant phyllodes showed the reverse pattern of p16 loss with diffuse strong Rb (p16-/diffuse Rb+). phyllodes 37-46 cyclin dependent kinase inhibitor 2A Homo sapiens 123-126 23916291-8 2013 Twenty-nine percent (4/14) malignant phyllodes showed diffuse strong p16 labeling with Rb loss in malignant cells (diffuse p16+/Rb-), whereas 21% (3/14) malignant phyllodes showed the reverse pattern of p16 loss with diffuse strong Rb (p16-/diffuse Rb+). phyllodes 37-46 cyclin dependent kinase inhibitor 2A Homo sapiens 123-126 23916291-8 2013 Twenty-nine percent (4/14) malignant phyllodes showed diffuse strong p16 labeling with Rb loss in malignant cells (diffuse p16+/Rb-), whereas 21% (3/14) malignant phyllodes showed the reverse pattern of p16 loss with diffuse strong Rb (p16-/diffuse Rb+). phyllodes 37-46 cyclin dependent kinase inhibitor 2A Homo sapiens 123-126 23916291-13 2013 Ki-67 was highest in malignant phyllodes with diffuse p16+/Rb- labeling. phyllodes 31-40 cyclin dependent kinase inhibitor 2A Homo sapiens 54-57 23916291-14 2013 In summary, 50% malignant phyllodes display evidence of Rb/p16 pathway alterations, likely reflecting p16 or Rb inactivation. phyllodes 26-35 cyclin dependent kinase inhibitor 2A Homo sapiens 59-62 23916291-14 2013 In summary, 50% malignant phyllodes display evidence of Rb/p16 pathway alterations, likely reflecting p16 or Rb inactivation. phyllodes 26-35 cyclin dependent kinase inhibitor 2A Homo sapiens 102-105 20497245-0 2010 p16 and pRb immunohistochemical expression increases with increasing tumour grade in mammary phyllodes tumours. phyllodes 93-102 cyclin dependent kinase inhibitor 2A Homo sapiens 0-3