PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11392533-4 2001 The present study was undertaken to examine the general utility of AzaTyr as a structural motif for PTP inhibitor design by examining the phospho-azatyrosine (pAzaTyr)-containing peptide Ac-Asp-Ala-Asp-Glu-pAzaTyr-Leu-amide (8) in a PTP1 enzyme system. beta-(5-hydroxy-2-pyridyl)alanine 67-73 protein tyrosine phosphatase receptor type U Homo sapiens 100-103 11392533-7 2001 The much lower PTP affinity of the pAzaTyr-containing peptide reduces the potential utility of the AzaTyr pharmacophore for PTP inhibitor design. beta-(5-hydroxy-2-pyridyl)alanine 36-42 protein tyrosine phosphatase receptor type U Homo sapiens 15-18 11392533-7 2001 The much lower PTP affinity of the pAzaTyr-containing peptide reduces the potential utility of the AzaTyr pharmacophore for PTP inhibitor design. beta-(5-hydroxy-2-pyridyl)alanine 36-42 protein tyrosine phosphatase receptor type U Homo sapiens 124-127