PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23851366-10 2013 At the mechanistic level, trehalose treatment led to a significant upregulation in the expression of key autophagy-related genes at the mRNA level including Lc3, Becn1, Sqstm1 and Atg5. Trehalose 26-35 beclin 1, autophagy related Mus musculus 162-167 33197516-7 2021 Moreover, in TBHP-treated NSC34 cells, trehalose promoted the expression of autophage-related markers (LC3 and Beclin-1), concomitant with decreased levels of apoptosis. Trehalose 39-48 beclin 1, autophagy related Mus musculus 111-119 29996716-7 2018 In contrast, we found that trehalose action on thermogenesis was independent of LEP (leptin) and the autophagy pathway, as there was robust thermogenic induction in trehalose-treated ob/ob, Becn1, Atg16l1, and Epg5 mutant mice. Trehalose 27-36 beclin 1, autophagy related Mus musculus 190-195 23644913-7 2013 RESULTS: Chronic administration of trehalose resulted in a reduction of frontal cortex p62/beclin-1 ratio suggesting enhancement of autophagy. Trehalose 35-44 beclin 1, autophagy related Mus musculus 91-99