PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12904065-5 2003 The sulfamide and sulfonamide derivatization at the N-terminal position in general afforded highly potent thrombin inhibitors but with moderate oral absorption, while the well-absorbable N-carbamate derivatives exhibited limited metabolic stability in S9 fractions. fusarubin 4-13 coagulation factor II Rattus norvegicus 106-114