PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18217703-4 2008 An extensive SAR study led to sulfamide (R)- 22b, which inhibited the strand transfer with an IC50 of 7 nM and HIV infection in MT4 cells with a CIC95 of 44 nM, and ketoamide (S)- 28c that inhibited strand transfer with an IC50 of 12 nM and the HIV infection in MT4 cells with a CIC95 of 13 nM and exhibited a good pharmacokinetic profile when dosed orally to preclinical species. fusarubin 30-39 sarcosine dehydrogenase Homo sapiens 13-16 22506561-3 2012 The SAR for steroid inhibition of G6PD has been substantially developed; the 3beta-alcohol can be replaced with 3beta-H-bond donors such as sulfamide, sulfonamide, urea, and carbamate. fusarubin 140-149 sarcosine dehydrogenase Homo sapiens 4-7