PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24224693-2 2013 Especially when a sulfonamide or sulfamide moiety was added, resulting compounds exhibited not only potent CB1R activity but also a desired tPSA value over 90 A(2), a threshold considered to possess a low probability to cross BBB, leading to the identification of compound 4 (B/P = 1/64) as a peripherally restricted CB1R antagonist. fusarubin 33-42 cannabinoid receptor 1 (brain) Mus musculus 107-111 24224693-2 2013 Especially when a sulfonamide or sulfamide moiety was added, resulting compounds exhibited not only potent CB1R activity but also a desired tPSA value over 90 A(2), a threshold considered to possess a low probability to cross BBB, leading to the identification of compound 4 (B/P = 1/64) as a peripherally restricted CB1R antagonist. fusarubin 33-42 cannabinoid receptor 1 (brain) Mus musculus 317-321