PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26961327-0 2016 Tenascin C affects mineralization of SaOS2 osteoblast-like cells through matrix vesicles. saos2 37-42 tenascin C Homo sapiens 0-10 26961327-5 2016 In this study, we demonstrated that the expression level of TNC was increased with osteoblast differentiation of osteoblast-like SaOS2 cells, and down-regulation of TNC expression by siRNA could significantly inhibit SaOS2 differentiation toward osteoblasts and mineralization as evidenced by decreases in ALP activity, mineralized nodule formation, calcium deposition, and down-regulation of osteogenic marker genes ALP, and COL1A1. saos2 129-134 tenascin C Homo sapiens 60-63