PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15988024-8	2005	Despite their separate functions in silencing and SAGA-mediated transcription, respectively, deletion of both UBP10 and UBP8 results in a synergistic increase in the steady-state levels of H2B ubiquitination and in the number of genes with altered expression, indicating that Ubp10p and Ubp8p likely overlap in some of their target chromatin regions.	ubp8	120-124	H2B clustered histone 21	Homo sapiens	189-192	
26912860-3	2016	The crystal structure of the Ubp8/Sgf11/Sus1/Sgf73 DUB module bound to a ubiquitinated nucleosome reveals that the DUB module primarily contacts H2A/H2B, with an arginine cluster on the Sgf11 zinc finger domain docking on the conserved H2A/H2B acidic patch.	ubp8	29-33	H2B clustered histone 21	Homo sapiens	149-152	
26912860-3	2016	The crystal structure of the Ubp8/Sgf11/Sus1/Sgf73 DUB module bound to a ubiquitinated nucleosome reveals that the DUB module primarily contacts H2A/H2B, with an arginine cluster on the Sgf11 zinc finger domain docking on the conserved H2A/H2B acidic patch.	ubp8	29-33	H2B clustered histone 21	Homo sapiens	240-243	
26912860-4	2016	The Ubp8 catalytic domain mediates additional contacts with H2B, as well as with the conjugated ubiquitin.	ubp8	4-8	H2B clustered histone 21	Homo sapiens	60-63	
17643376-0	2007	H2B ubiquitylation acts as a barrier to Ctk1 nucleosomal recruitment prior to removal by Ubp8 within a SAGA-related complex.	ubp8	89-93	H2B clustered histone 21	Homo sapiens	0-3	
17643376-2	2007	We previously studied histone H2B ubiquitylation on lysine 123 and subsequent deubiquitylation by SAGA-associated Ubp8.	ubp8	114-118	H2B clustered histone 21	Homo sapiens	30-33	
14563679-5	2003	We show that Ubp8, a component of the SAGA acetylation complex, is required for SAGA-mediated deubiquitylation of histone H2B in vitro.	ubp8	13-17	H2B clustered histone 21	Homo sapiens	122-125	
14563679-6	2003	Loss of Ubp8 in vivo increased both gene-associated and overall cellular levels of ubiquitylated H2B.	ubp8	8-12	H2B clustered histone 21	Homo sapiens	97-100	
14563679-8	2003	In addition, disruption of either ubiquitylation or Ubp8-mediated deubiquitylation of H2B resulted in altered levels of gene-associated H3 Lys 4 methylation and Lys 36 methylation, which have both been linked to transcription.	ubp8	52-56	H2B clustered histone 21	Homo sapiens	86-89	
15657442-3	2005	The recent finding that the removal of the ubiquitin group from H2B is performed by a component of SAGA, Ubp8, is intriguing as it assigns two posttranslation modification processes to one complex.	ubp8	105-109	H2B clustered histone 21	Homo sapiens	64-67