PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8331574-2 1993 The formation of 5-hydroxyomeprazole and omeprazole sulfone (OPZ-SFN) from OPZ exhibited a biphasic kinetic behavior, indicating that at least two distinct enzymes are involved in either of the metabolic pathways of OPZ. omeprazole sulfone 41-59 RNA exonuclease 2 Homo sapiens 65-68 16276979-3 2005 5-Hyroxyomeprazole (5-OHOMP) and omeprazole sulfone (OMP-SFN) are the two major metabolites of OMP in human. omeprazole sulfone 33-51 RNA exonuclease 2 Homo sapiens 57-60 9275713-1 1996 In the present study, a specific and reliable method was developed for the determination of omeprazole and its two major metabolites, hydroxyomeprazole (OH-OPZ) and omeprazole sulfone (OPZ-SFN) in Chinese adult human liver microsome by reversed phase HPLC assay. omeprazole sulfone 165-183 RNA exonuclease 2 Homo sapiens 189-192 1429977-2 1992 A reversed-phase high-performance liquid chromatographic method was developed that enables concentrations of OPZ and its major metabolites, omeprazole sulphone (OPZ-SFN) and hydroxy-omeprazole (H-OPZ), to be determined simultaneously in plasma and that of H-OPZ in urine. omeprazole sulfone 140-159 RNA exonuclease 2 Homo sapiens 165-168