PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10820001-1 2000 Transition state analogue boronic acid inhibitors mimicking the structures and interactions of good penicillin substrates for the TEM-1 beta-lactamase of Escherchia coli were designed using graphic analyses based on the enzyme"s 1.7 A crystallographic structure. Boronic Acids 26-38 TEM-1 beta-lactamase Escherichia coli 130-150