PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29784271-0 2018 Boronic acid inhibitors of the class A beta-lactamase KPC-2. Boronic Acids 0-12 UBA domain containing 1 Homo sapiens 54-59 22330909-4 2012 The first complex is that of a small boronic acid compound, 3-nitrophenyl boronic acid (3-NPBA), bound to KPC-2 with 1.62-A resolution. Boronic Acids 37-49 UBA domain containing 1 Homo sapiens 106-111 29784271-4 2018 We report the design and synthesis of novel boronic acid transition state analogs containing a 1,4-substituted 1,2,3-triazole linker based on the known inhibitor 3-nitrophenyl boronic acid and demonstrate that they are promising scaffolds for the development inhibitors of KPC-2 with the ability to recover sensitivity to the antibiotic cefotaxime. Boronic Acids 44-56 UBA domain containing 1 Homo sapiens 273-278 26729491-0 2016 Crystal Structures of KPC-2 and SHV-1 beta-Lactamases in Complex with the Boronic Acid Transition State Analog S02030. Boronic Acids 74-86 UBA domain containing 1 Homo sapiens 22-27