PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19912934-4	1993	The levels of adrenal TH mRNA were increased 1 h after CHX and had increased by approximately threefold over saline control [from 3.85 +/- 0.4 (SE) to 11.5 +/- 2 (SE) pg/mug RNA] at 6 h after treatment.	Sodium Chloride	109-115	tyrosine hydroxylase	Rattus norvegicus	22-24	
1694105-2	1990	After prolonged administration of 2% sodium chloride as drinking water (salt-loading), the treatment increased the levels of VP, OXY, TH, GAL, DYN and CCK mRNA in the PVN and SON.	Sodium Chloride	37-52	tyrosine hydroxylase	Rattus norvegicus	134-136	
2897232-8	1988	In animals that drank water, 10 mM, 30 mM, and 100 mM NaCl, the amounts (pmol) of TH were, respectively, 0.28 +/- 0.03, 0.31 +/- 0.04, 0.23 +/- 0.02, and 0.21 +/- 0.01 per ME and 0.67 +/- 0.06, 0.72 +/- 0.11, 0.37 +/- 0.01, and 0.34 +/- 0.02 per SCG.	Sodium Chloride	54-58	tyrosine hydroxylase	Rattus norvegicus	82-84	
6115031-0	1981	Whole brain tyrosine hydroxylase activity during the development of deoxycorticosterone acetate-1% sodium chloride-induced hypertension in rats.	Sodium Chloride	99-114	tyrosine hydroxylase	Rattus norvegicus	12-32	
2897232-0	1988	Saline ingestion stimulates the in situ molar activity of tyrosine hydroxylase in the median eminence and superior cervical ganglion.	Sodium Chloride	0-6	tyrosine hydroxylase	Rattus norvegicus	58-78	
2897232-4	1988	In rats that drank 10 mM, 30 mM, and 100 mM NaCl for 7 days, TH activity in the ME was 34 +/- 4, 36 +/- 5, and 45 +/- 3 (mean and S.E.M.)	Sodium Chloride	44-48	tyrosine hydroxylase	Rattus norvegicus	61-63	
2897232-6	1988	The activity of TH in the SCG of animals that drank 10 mM, 30 mM, and 100 mM NaCl was 143 +/- 24, 167 +/- 12, and 272 +/- 13 mol DOPA.h-1.mol TH-1, respectively, compared to 119 +/- 10 for animals that drank water.	Sodium Chloride	77-81	tyrosine hydroxylase	Rattus norvegicus	16-18	
2897232-7	1988	The mass of TH in the ME and SCG decreased as a function of the concentration of NaCl in the drinking water.	Sodium Chloride	81-85	tyrosine hydroxylase	Rattus norvegicus	12-14	
6741741-4	1984	A significant increase of TH immunoreactivity was also detected in the substantia nigra: GM1 prevented the disappearance of TH-positive cell bodies and increased the formation of TH-positive collaterals and dendrites with respect to the saline treatment.	Sodium Chloride	237-243	tyrosine hydroxylase	Rattus norvegicus	26-28	
12654507-8	2003	Mapping of brain regions in saline control rats agreed with previous studies, including showing the presence of low abundance TH mRNA and the absence of DAT mRNA in the caudate-putamen.	Sodium Chloride	28-34	tyrosine hydroxylase	Rattus norvegicus	126-128	
436936-2	1979	In the rat, both acute and chronic saline loading stimulated urinary CA excretion without affecting blood pressure; adrenal tyrosine hydroxylase (TH) activity was increased.	Sodium Chloride	35-41	tyrosine hydroxylase	Rattus norvegicus	124-144	
237779-0	1975	Dopamine beta-hydroxylase and tyrosine hydroxylase activities in spontaneously hypertensive rats after NaCl administration.	Sodium Chloride	103-107	tyrosine hydroxylase	Rattus norvegicus	30-50	
16324736-5	2005	In locus coeruleus (LC), restraint stress elevated TH and DBH mRNA in saline-, but not in nicotine-infused rats.	Sodium Chloride	70-76	tyrosine hydroxylase	Rattus norvegicus	51-53	
12963419-0	2003	Ganglionic tyrosine hydroxylase and norepinephrine transporter are decreased by increased sodium chloride in vivo and in vitro.	Sodium Chloride	90-105	tyrosine hydroxylase	Rattus norvegicus	11-31	
12963419-2	2003	Increasing dietary salt (from 0.02% to 1%, 4% or 8% NaCl in rat chow) decreased (p<0.05) the mRNA levels of tyrosine hydroxylase and the norepinephrine transporter in the adrenal gland, superior cervical ganglia and celiac ganglia.	Sodium Chloride	52-56	tyrosine hydroxylase	Rattus norvegicus	111-131	
12963419-4	2003	To test the hypothesis that NaCl acts directly on postganglionic neurons to suppress the expression of these proteins, it was determined if increases in NaCl concentrations, of a magnitude achieved during increases in dietary salt in vivo, suppress expression of tyrosine hydroxylase and the norepinephrine transporter in cultured sympathetic neurons in vitro.	Sodium Chloride	28-32	tyrosine hydroxylase	Rattus norvegicus	263-283	
12963419-4	2003	To test the hypothesis that NaCl acts directly on postganglionic neurons to suppress the expression of these proteins, it was determined if increases in NaCl concentrations, of a magnitude achieved during increases in dietary salt in vivo, suppress expression of tyrosine hydroxylase and the norepinephrine transporter in cultured sympathetic neurons in vitro.	Sodium Chloride	153-157	tyrosine hydroxylase	Rattus norvegicus	263-283	
12963419-6	2003	In addition, NaCl added to cultured neurons decreased tyrosine hydroxylase and norepinephrine transporter protein and mRNA levels, and norepinephrine uptake; however, the NaCl concentration increases required were 15-30 mEq l(-1).	Sodium Chloride	13-17	tyrosine hydroxylase	Rattus norvegicus	54-74	
11284443-10	2001	The mRNA for tyrosine hydroxylase (TH) in substantia nigra + ventral tegmental area was significantly elevated to about 140% of saline controls both in the "repeated cocaine" and the "acute cocaine" group as compared with the "saline group".	Sodium Chloride	128-134	tyrosine hydroxylase	Rattus norvegicus	13-33	
11284443-10	2001	The mRNA for tyrosine hydroxylase (TH) in substantia nigra + ventral tegmental area was significantly elevated to about 140% of saline controls both in the "repeated cocaine" and the "acute cocaine" group as compared with the "saline group".	Sodium Chloride	227-233	tyrosine hydroxylase	Rattus norvegicus	13-33	
10771110-8	2000	Tyrosine hydroxylase (TH) immunocytochemistry revealed that TH positive DA fiber density in the striatum and the number of DA cell bodies in the substantia nigra were greater in animals receiving 10 or 100 microg of GDNF than those receiving saline.	Sodium Chloride	242-248	tyrosine hydroxylase	Rattus norvegicus	0-20	
9694971-5	1998	Interestingly, TH-immunopositive cell bodies were observed 4 months after amphetamine in the lateral caudate/putamen, defined anteriorly by the genu of the corpus collosum and posteriorly by the junction of the anterior commissures; these striatal TH-positive cells were not observed in saline- or amphetamine-treated rats that did not become hyperthermic.	Sodium Chloride	287-293	tyrosine hydroxylase	Rattus norvegicus	15-17