PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22216975-9 2012 RESULTS: Saline-treated animals showed intense epithelial staining for Bcl-xL and a faint labelling for both Bax and Caspase-3. Sodium Chloride 9-15 caspase 3 Rattus norvegicus 117-126 26009821-10 2015 Moreover, methane-rich saline reduced the amount of caspase-3 and the number of apoptotic cells. Sodium Chloride 23-29 caspase 3 Rattus norvegicus 52-61 21416227-8 2011 The activity of caspase 3 was significantly increased in the saline treated group. Sodium Chloride 61-67 caspase 3 Rattus norvegicus 16-25 20067106-5 2009 RESULTS: Compared with saline group, apoptosis neurons were detected at the related brain regions (such as frontal cortex, hippocampus and striatum) of the rats in MDMA treated groups; Expression of Caspase-3 and CytC was observed at different level. Sodium Chloride 23-29 caspase 3 Rattus norvegicus 199-208 19781374-7 2009 RESULTS: The rats in group 2 that received saline only showed neurological impairment as well as elevated mortality, and were found to have significantly increased levels of MDA and caspase-3, but reduced SOD activities in brain tissues (P < 0.05). Sodium Chloride 43-49 caspase 3 Rattus norvegicus 182-191 17888399-6 2007 Saline-treated kidneys had increased creatinine and BUN, and exhibited tubular epithelial apoptosis with activated caspase 3 expression. Sodium Chloride 0-6 caspase 3 Rattus norvegicus 115-124 15686660-9 2004 In contrast, caspase 3 was lower at 24 hours among the hemin-pretreated group compared with saline-treated liver transplant controls. Sodium Chloride 92-98 caspase 3 Rattus norvegicus 13-22 15307903-10 2004 Activated caspase-3 immunocytochemistry indicated apoptosis was quite prominent in motor neurons in vehicle (saline) controls, but was dramatically reduced by rTM. Sodium Chloride 109-115 caspase 3 Rattus norvegicus 10-19 12473384-1 2003 Eighteen and twenty-four hours after intraperitoneal administration of D-galactosamine (1g/kg body weight) to rats, the activity of caspase-3-like protease in the liver increased significantly compared with that in the control group given saline. Sodium Chloride 239-245 caspase 3 Rattus norvegicus 132-141 30517338-7 2018 RESULTS: There was a significant decrease in inflammation-neutrophil count and intercellular adhesion molecule-1 (ICAM-1) expression in lung parenchyma were higher in the saline group in comparison with the MB group-and in apoptosis-caspase-3 expression was higher in the saline group and Bcl-2 expression was higher in MB group. Sodium Chloride 171-177 caspase 3 Rattus norvegicus 233-242 28663674-8 2017 RESULTS: BDL-saline group showed significant over-expression of BCL2, caspase3 and Fas. Sodium Chloride 13-19 caspase 3 Rattus norvegicus 70-78 20385118-5 2010 In saline-treated ischemic rats there was an increase in TNF-alpha levels and in the activity of JNK and caspase-3 accompanied, despite an appreciable ERK 1/2 activation, by a large infarct size. Sodium Chloride 3-9 caspase 3 Rattus norvegicus 105-114 19596825-4 2009 Intraperitoneal injection of hydrogen-rich saline before reperfusion significantly decreased plasma and myocardium malondialdehyde (MDA) concentration, decreased cardiac cell apoptosis, and myocardial 8-hydroxydeoxyguanosine (8-OHdG) in area at risk zones (AAR), suppressed the activity of caspase-3, and reduced infarct size. Sodium Chloride 43-49 caspase 3 Rattus norvegicus 290-299 19170187-8 2009 The cholinergic activation reduces cytosolic levels of cytochrome C, suggesting an improved stability of the mitochondrial membrane, and the expression level of the active caspase 3 fragments (19, 16 kDa) is reduced significantly with respect to saline treatment. Sodium Chloride 246-252 caspase 3 Rattus norvegicus 172-181 19018269-4 2009 In the striatum and liver of saline-treated control rats, the activation of extracellular signal-regulated kinases, c-jun N-terminal kinases, and caspase-3, the increase in tumor necrosis factor-alpha (TNF-alpha) concentration and DNA fragmentation, as well as the increase in TNF-alpha plasma levels, occurred 10 and 20 h after the ischemic insult suggesting an activation of inflammatory and apoptotic responses. Sodium Chloride 29-35 caspase 3 Rattus norvegicus 116-155 16030430-3 2005 Animals administered MNNG followed by S-NaCl developed squamous cell carcinomas of the stomach associated with increased Bcl-2 expression and decreased expression of Bax, Bim, caspase 8 and caspase 3. Sodium Chloride 38-44 caspase 3 Rattus norvegicus 190-199 15111328-9 2004 Using an antibody that recognizes the active form caspase-3, we observed an increment in caspase-3 activation in rats receiving BSA with respect to those receiving saline. Sodium Chloride 164-170 caspase 3 Rattus norvegicus 50-59 15111328-9 2004 Using an antibody that recognizes the active form caspase-3, we observed an increment in caspase-3 activation in rats receiving BSA with respect to those receiving saline. Sodium Chloride 164-170 caspase 3 Rattus norvegicus 89-98 33996809-5 2021 Middle and high doses (50 and 100 mM) of NaCl increased the level of cleaved-caspase 3/caspase 3, cleaved-caspase 8/caspase 8, Bax/Bcl2, LC3 II/LC3 I, Beclin-1, and ATG7 in H9C2 cells and NRCM. Sodium Chloride 41-45 caspase 3 Rattus norvegicus 77-86 33996809-8 2021 NO donor sodium nitroprusside (SNP) reversed the increases of cleaved-caspase 3/caspase 3, cleaved-caspase 8/caspase 8, Bax/Bcl2 induced by NaCl (100 mM) in H9C2 cells and NRCM. Sodium Chloride 140-144 caspase 3 Rattus norvegicus 70-79 27881053-10 2017 The sciatic nerves of saline-treated rats showed considerable increase in bax, caspase 3 and caspase 8 expressions (p < 0.001) while OT treatment significantly suppressed these apoptosis markers. Sodium Chloride 22-28 caspase 3 Rattus norvegicus 79-88 26829459-10 2016 Compared to control rats, skin MPO activity, MDA and caspase-3 levels were increased similarly in saline-treated normo- and hyperglycemic rats. Sodium Chloride 98-104 caspase 3 Rattus norvegicus 53-62 23953793-6 2013 RESULTS: Compared with the saline + sham group, the saline + I/R group had significant increases in Bax, p53, Bax/Bcl-2 ratio, caspase 3, IL-6, TNF-alpha, and W/D weight ratio but a decrease in Bcl-2 (P < 0.05). Sodium Chloride 52-58 caspase 3 Rattus norvegicus 127-136 24937348-11 2014 In addition, hydrogen-rich saline treatment reduced caspase-3 activity in cortex and hippocampus after cardiac arrest/resuscitation. Sodium Chloride 27-33 caspase 3 Rattus norvegicus 52-61 24360058-10 2014 Caspase-3 expression was only observed in ovarian surface epithelium in the saline and montelukast groups. Sodium Chloride 76-82 caspase 3 Rattus norvegicus 0-9 24360058-11 2014 However, the mean caspase-3 expression score was higher in the saline group than the montelukast group (p<0.001). Sodium Chloride 63-69 caspase 3 Rattus norvegicus 18-27 24077857-3 2014 Expression of c-Jun activating transcription factor 3 and caspase-3 was absent or infrequent in the TG, and cranial sensory and motor nuclei of saline- and prednisolone-treated animals. Sodium Chloride 144-150 caspase 3 Rattus norvegicus 58-67 26199614-5 2015 Results at 24 hours, 48 hours, 1 week and 2 weeks after injury showed that hydrogen-rich saline markedly reduced cell death, inflammatory cell infiltration, serum malondialdehyde content, and caspase-3 immunoreactivity, elevated serum superoxide dismutase activity and calcitonin gene-related peptide immunoreactivity, and improved motor function in the hindlimb. Sodium Chloride 89-95 caspase 3 Rattus norvegicus 192-201 25039564-8 2014 In the saline-treated irradiation groups, myeloperoxidase and caspase-3 activities, 8-OHdG and TNF-alpha levels were found to be increased in both tissues (p < 0.05). Sodium Chloride 7-13 caspase 3 Rattus norvegicus 62-71 23899611-11 2013 Caspase-3 expression was only detected in the ovarian surface epithelium in all groups, and there was a significant difference between the treatment groups and the saline group (p < 0.0001). Sodium Chloride 164-170 caspase 3 Rattus norvegicus 0-9 23514721-10 2013 In the P3 saline group, activated caspase-3 (mean+-SEM per lumbar cord section 6.1+-0.3) and Fluoro-Jade C (12.1+-1.2) counts were higher than at P7, but were not altered by levobupivacaine (P=0.62 and P=0.11, two-tailed Mann-Whitney test). Sodium Chloride 10-16 caspase 3 Rattus norvegicus 34-43 27385959-9 2013 Caspase-3 and PARP increased during AS and SS in saline- or morphine-treated animals. Sodium Chloride 49-55 caspase 3 Rattus norvegicus 0-9 22642649-10 2012 After siRNA treatment, the amount of caspase-3 mRNA was significantly lower when compared to the saline control group. Sodium Chloride 97-103 caspase 3 Rattus norvegicus 37-46 22809912-11 2012 Caspase-3 activity was increased after controlled mechanical ventilation with saline by 55% (p<.05), while it remained similar to control animals in mechanically ventilated animals receiving an injection of bortezomib. Sodium Chloride 78-84 caspase 3 Rattus norvegicus 0-9