PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8542262-5 1995 In this study, ten patients with hydralazine-induced vasculitis had antibodies with specificities for both myeloperoxidase and lactoferrin. Hydralazine 33-44 myeloperoxidase Homo sapiens 107-122 10693882-2 2000 However, there have been reports suggesting that hydralazine, propylthiouracil, and several other drugs may cause some cases of APV, and the majority of these cases have been associated with antimyeloperoxidase (anti-MPO) ANCA. Hydralazine 49-60 myeloperoxidase Homo sapiens 217-220 10693882-4 2000 METHODS: In this study, we determined the prevalence of exposure to hydralazine, propylthiouracil, and other drugs previously implicated in APV among 30 patients with vasculitis and the highest titers of anti-MPO antibodies newly detected in our laboratory between 1994 and 1998. Hydralazine 68-79 myeloperoxidase Homo sapiens 209-212 10693882-13 2000 CONCLUSION: These data suggest that a sizable proportion of cases of APV with high titers of anti-MPO antibodies are drug-associated, especially following exposure to hydralazine or propylthiouracil. Hydralazine 167-178 myeloperoxidase Homo sapiens 98-101 8248010-0 1993 Interaction of myeloperoxidase and elastase enzyme activity with the antihypertensive agents hydralazine and dihydralazine. Hydralazine 93-104 myeloperoxidase Homo sapiens 15-30 7946512-0 1994 Occurrence of autoantibodies directed against myeloperoxidase and elastase in patients treated with hydralazine and presenting with glomerulonephritis. Hydralazine 100-111 myeloperoxidase Homo sapiens 46-61 8248010-1 1993 Autoantibodies directed against myeloperoxidase and elastase have been found in patients developing hydralazine-induced lupus and hydralazine-induced isolated glomerulonephritis. Hydralazine 100-111 myeloperoxidase Homo sapiens 32-60 8248010-1 1993 Autoantibodies directed against myeloperoxidase and elastase have been found in patients developing hydralazine-induced lupus and hydralazine-induced isolated glomerulonephritis. Hydralazine 130-141 myeloperoxidase Homo sapiens 32-60 8248010-2 1993 The aim of this study was to investigate influence of hydralazine and dihydralazine upon myeloperoxidase and elastase enzyme activity. Hydralazine 54-65 myeloperoxidase Homo sapiens 89-104 8248010-3 1993 Using a 4-aminoantipyrin in vitro system, dihydralazine was 2.5 times as potent in inhibiting myeloperoxidase activity as compared to hydralazine. Hydralazine 44-55 myeloperoxidase Homo sapiens 94-109 2173810-5 1990 By contrast, anti-MPO was found in a majority of vasculitis patients without extrarenal symptoms (6/9), including 3 patients treated with hydralazine. Hydralazine 138-149 myeloperoxidase Homo sapiens 18-21 2168822-5 1990 In another group of six patients with a SLE-like syndrome induced by anti-hypertensive treatment with the anti-hypertensive hydralazine, anti-MPO antibodies occurred in all six, and anti-elastase antibodies in five. Hydralazine 124-135 myeloperoxidase Homo sapiens 142-145 1337335-1 1992 Two mouse-human heterohybridomas secreting human antibodies to myeloperoxidase (MPO) were derived from the peripheral blood of a patient who developed microscopic polyarteritis as the result of long-term treatment with hydralazine. Hydralazine 219-230 myeloperoxidase Homo sapiens 63-78 1337335-1 1992 Two mouse-human heterohybridomas secreting human antibodies to myeloperoxidase (MPO) were derived from the peripheral blood of a patient who developed microscopic polyarteritis as the result of long-term treatment with hydralazine. Hydralazine 219-230 myeloperoxidase Homo sapiens 80-83 1664857-6 1991 Oxidation of hydralazine catalyzed by myeloperoxidase (MPO) produced the same metabolites and covalent binding to protein. Hydralazine 13-24 myeloperoxidase Homo sapiens 38-53 1664857-6 1991 Oxidation of hydralazine catalyzed by myeloperoxidase (MPO) produced the same metabolites and covalent binding to protein. Hydralazine 13-24 myeloperoxidase Homo sapiens 55-58 1657003-0 1991 The antihypertensive compounds hydralazine, dihydralazine and cadralazine and their metabolites inhibit myeloperoxidase activity as measured by chemiluminescence. Hydralazine 31-42 myeloperoxidase Homo sapiens 104-119 1848881-0 1991 Antibodies to neutrophil granulocyte myeloperoxidase and elastase: autoimmune responses in glomerulonephritis due to hydralazine treatment. Hydralazine 117-128 myeloperoxidase Homo sapiens 37-65 1848881-1 1991 Autoantibodies against myeloperoxidase and elastase were found in a study of nine patients who had developed glomerulonephritis after treatment with hydralazine, but not in patients who were treated with hydralazine without side-effects. Hydralazine 149-160 myeloperoxidase Homo sapiens 23-51 2173810-6 1990 One of the patients treated with hydralazine had circulating ANCA in combination with anti-MPO. Hydralazine 33-44 myeloperoxidase Homo sapiens 91-94 30369391-0 2018 Hydralazine-induced MPO-ANCA Renal-Limited Vasculitis Masquerading as Lupus Nephritis. Hydralazine 0-11 myeloperoxidase Homo sapiens 20-23 29929470-4 2018 CASE PRESENTATION: A 79-year-old Japanese woman developed hydralazine-induced pauci-immune necrotizing crescentic glomerulonephritis with MPO-ANCA. Hydralazine 58-69 myeloperoxidase Homo sapiens 138-141 25210633-0 2014 Hydralazine induces myeloperoxidase and proteinase 3 anti-neutrophil cytoplasmic antibody vasculitis and leads to pulmonary renal syndrome. Hydralazine 0-11 myeloperoxidase Homo sapiens 20-35