PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2851438-2 1988 The levels of plasma vasopressin, ACTH and corticosterone increased after the administration of lithium (LiCl 4 mmol/kg BW, 11 days) in rats, while the tissue vasopressin concentration in the median eminence, the rest of the hypothalamus and the posterior pituitary was decreased. Lithium 96-103 arginine vasopressin Rattus norvegicus 21-32 2851438-5 1988 Lithium stimulated ACTH secretion per se and also enhanced vasopressin-induced ACTH secretion in cultured pituitary cells and in half pituitary incubations, while it did not affect CRF-induced ACTH secretion. Lithium 0-7 arginine vasopressin Rattus norvegicus 59-70 2851438-8 1988 Thus, it is possible that lithium stimulates ACTH release by acting directly on the corticotroph, stimulating vasopressin release and potentiating vasopressin-induced ACTH release. Lithium 26-33 arginine vasopressin Rattus norvegicus 110-121 2851438-8 1988 Thus, it is possible that lithium stimulates ACTH release by acting directly on the corticotroph, stimulating vasopressin release and potentiating vasopressin-induced ACTH release. Lithium 26-33 arginine vasopressin Rattus norvegicus 147-158 2454589-9 1988 It is postulated that lithium stimulates vasopressin release from the central nervous system and that elevated plasma vasopressin potentiates PGE2 production in the kidney synergistically with lithium. Lithium 193-200 arginine vasopressin Rattus norvegicus 118-129 2454589-0 1988 Involvement of prostaglandin E2, cAMP, and vasopressin in lithium-induced polyuria. Lithium 58-65 arginine vasopressin Rattus norvegicus 43-54 2454589-4 1988 The in vitro data of the intact rat kidney showed that lithium stimulated arginine vasopressin (AVP)-induced PGE2 production and suggested that PGE2 suppressed cAMP synthesis in rat renal medulla. Lithium 55-62 arginine vasopressin Rattus norvegicus 83-94 2454589-9 1988 It is postulated that lithium stimulates vasopressin release from the central nervous system and that elevated plasma vasopressin potentiates PGE2 production in the kidney synergistically with lithium. Lithium 22-29 arginine vasopressin Rattus norvegicus 41-52 3040254-4 1987 The increased volume of both principal and intercalated cells seems to be part of a general hyperplasia and hyperactivity of the collecting duct, which may in some way be related to the effects of lithium on vasopressin-mediated mediated water transport. Lithium 197-204 arginine vasopressin Rattus norvegicus 208-219 2835449-4 1988 When added to rat brain septal slices that had been prelabeled with 3H-myo-inositol, vasopressin stimulated the accumulation of 3H-inositol-1-phosphate (IP1) in the presence of 7 mM lithium. Lithium 182-189 arginine vasopressin Rattus norvegicus 85-96 3224025-0 1988 Early renal changes in lithium-treated normal and vasopressin-deficient rats. Lithium 23-30 arginine vasopressin Rattus norvegicus 50-61 870586-0 1977 Prostaglandin A2 at low rates of infusion restores the antidiuretic effect of vasopressin in lithium-treated rats. Lithium 93-100 arginine vasopressin Rattus norvegicus 78-89 577109-6 1977 The experiments show that when vasopressin-induced alterations of the urine flow are excluded and when the sodium intake is not extremely low, proportionality may occur between the lithium clearance and the urine flow. Lithium 181-188 arginine vasopressin Rattus norvegicus 31-42 7256183-0 1980 DDAVP (1-desamino-8-D-arginine-vasopressin) treatment of lithium-induced polyuria in the rat. Lithium 57-64 arginine vasopressin Rattus norvegicus 31-42 190861-0 1977 Antidiuretic and urinary cyclic AMP response of vasopressin in normal rats and in rats with lithium-polyuria. Lithium 92-99 arginine vasopressin Rattus norvegicus 48-59 190861-6 1977 The antidiuretic response to vasopressin was inhibited by 85% in 10 animals with marked polyuria induced by lithium administration (III). Lithium 108-115 arginine vasopressin Rattus norvegicus 29-40 190861-10 1977 Thus, the data suggest that the nephrogenic diabetes insipidus syndrome produced by lithium is associated with a defect in the renal formation of cyclic AMP in response to vasopressin. Lithium 84-91 arginine vasopressin Rattus norvegicus 172-183 177756-4 1976 Renal lithium content was increased substantially after the larger dose of PTH and was diminished slightly after db-cAMP and the larger dose of vasopressin. Lithium 6-13 arginine vasopressin Rattus norvegicus 144-155 188342-4 1976 Adenylate cyclase from the renal medulla of animals treated with ADH and lithium had a lower response to synthetic vasopressin in vitro than in animals treated with lithium alone. Lithium 73-80 arginine vasopressin Rattus norvegicus 115-126 188342-4 1976 Adenylate cyclase from the renal medulla of animals treated with ADH and lithium had a lower response to synthetic vasopressin in vitro than in animals treated with lithium alone. Lithium 165-172 arginine vasopressin Rattus norvegicus 115-126 177756-6 1976 These results indicate that lithium interferes with the phosphaturic responses to certain dosages of pth and vasopressin and suggest that renal lithium reabsorption and tissue lithium uptake may in part determine the extent of this cation-hormonal interaction. Lithium 28-35 arginine vasopressin Rattus norvegicus 109-120 988959-0 1976 Acute and chronic effects of vasopressin in rats with lithium-polyuria. Lithium 54-61 arginine vasopressin Rattus norvegicus 29-40 177756-7 1976 In addition, a competitive type of interaction between lithium and vasopressin is postulated. Lithium 55-62 arginine vasopressin Rattus norvegicus 67-78 4360856-5 1974 Rats receiving lithium (3-4 meq/kg/day) developed massive polyuria that was resistant to vasopressin, in comparison to rats with comparable polyuria induced by drinking glucose. Lithium 15-22 arginine vasopressin Rattus norvegicus 89-100 174768-0 1975 The effects of lithium ions on the antidiuretic action of vasopressin in the rat. Lithium 15-22 arginine vasopressin Rattus norvegicus 58-69 168279-0 1975 Renal effects of lithium administration in rats: alterations in water and electrolyte metabolism and the response to vasopressin and cyclic-adenosine monophosphate during prolonged administration. Lithium 17-24 arginine vasopressin Rattus norvegicus 117-128 1185624-0 1975 Proceedings: The lack of relationship between the concentration of lithium and the inhibition of the action of vasopressin by lithium in the rat. Lithium 126-133 arginine vasopressin Rattus norvegicus 111-122 166828-0 1975 Effects of lithium on vasopressin-dependent cyclic AMP in rat renal medulla. Lithium 11-18 arginine vasopressin Rattus norvegicus 22-33 166828-2 1975 For the pathogenic mechanism of the concentrating defect it has been postulated that lithium inhibits the vasopressin-dependent cyclic AMP system. Lithium 85-92 arginine vasopressin Rattus norvegicus 106-117 166828-4 1975 Therefore, the effect of lithium specifically on the vasopressin-dependent cyclic AMP system was investigated in rat renal medulla. Lithium 25-32 arginine vasopressin Rattus norvegicus 53-64 166828-5 1975 The increase of cyclic AMP concentration by vasopressin was inhibited by lithium. Lithium 73-80 arginine vasopressin Rattus norvegicus 44-55 166828-9 1975 These results suggest that lithium inhibits the vasopressin-dependent cyclic AMP concentration in renal medulla via the augmentation of its catabolism, rather than via the inhibition of cyclic AMP generation. Lithium 27-34 arginine vasopressin Rattus norvegicus 48-59 1202760-4 1975 These results indicate that lithium affects electrolyte transport in the same nephron segments in which the action of vasopressin is inhibitied. Lithium 28-35 arginine vasopressin Rattus norvegicus 118-129 4360856-9 1974 The present studies suggest that nephrogenic diabetes insipidus is a common finding after lithium treatment and results in part from interference with the mediation of vasopressin at a step distal to the formation of 3",5" cyclic AMP. Lithium 90-97 arginine vasopressin Rattus norvegicus 168-179 16495377-5 2006 This study demonstrated that the mouse cortical collecting duct mpkCCD(c14) cells are a good model; the deamino-8 D-arginine vasopressin (dDAVP)-induced endogenous AQP2 expression and plasma membrane localization was time-dependently reduced by treatment with clinically relevant lithium concentrations. Lithium 280-287 arginine vasopressin Rattus norvegicus 125-136 23408166-2 2013 Investigators have uncovered the intricate relationships of lithium with the vasopressin and aldosterone systems, and the membrane channels or transporters regulated by them. Lithium 60-67 arginine vasopressin Rattus norvegicus 77-88 25877068-3 2015 Lithium-induced NDI is due to resistance of the kidney to arginine vasopressin (AVP), leading to polyuria, natriuresis and kaliuresis. Lithium 0-7 arginine vasopressin Rattus norvegicus 67-78 16332930-1 2006 Lithium-induced nephrogenic diabetes insipidus (Li-NDI) is associated with increased urinary sodium excretion and decreased responsiveness to aldosterone and vasopressin. Lithium 0-7 arginine vasopressin Rattus norvegicus 158-169 16495377-8 2006 In vivo, kidney tissue of rats with lithium-induced NDI indeed generated less dDAVP-induced cAMP than that of controls, but this could be due to elevated blood AVP levels in rats with lithium-induced NDI. Lithium 36-43 arginine vasopressin Rattus norvegicus 80-83 16495377-8 2006 In vivo, kidney tissue of rats with lithium-induced NDI indeed generated less dDAVP-induced cAMP than that of controls, but this could be due to elevated blood AVP levels in rats with lithium-induced NDI. Lithium 184-191 arginine vasopressin Rattus norvegicus 80-83 7744515-2 1994 Lithium is known to antagonize vasopressin effects on fluid absorption in kidney distal nephrons. Lithium 0-7 arginine vasopressin Rattus norvegicus 31-42 11849454-6 2002 Vasopressin (100 pmol/L) increased UT-A1 phosphorylation in IMCD suspensions from control but not from lithium-fed rats; a higher vasopressin concentration (100 nmol/L) increased UT-A1 phosphorylation in control and lithium-fed rats. Lithium 216-223 arginine vasopressin Rattus norvegicus 0-11 11849454-6 2002 Vasopressin (100 pmol/L) increased UT-A1 phosphorylation in IMCD suspensions from control but not from lithium-fed rats; a higher vasopressin concentration (100 nmol/L) increased UT-A1 phosphorylation in control and lithium-fed rats. Lithium 216-223 arginine vasopressin Rattus norvegicus 130-141 8760265-0 1996 Effect of vasopressin on renal lithium reabsorption: a micropuncture and microperfusion study. Lithium 31-38 arginine vasopressin Rattus norvegicus 10-21 8760265-1 1996 Micropuncture techniques were used to investigate the nephron site(s) responsible for the vasopressin-induced reductions in lithium clearance and fractional lithium excretion (FELi) in anesthetized Brattleboro rats lacking endogenous vasopressin. Lithium 124-131 arginine vasopressin Rattus norvegicus 90-101 8760265-1 1996 Micropuncture techniques were used to investigate the nephron site(s) responsible for the vasopressin-induced reductions in lithium clearance and fractional lithium excretion (FELi) in anesthetized Brattleboro rats lacking endogenous vasopressin. Lithium 157-164 arginine vasopressin Rattus norvegicus 90-101 8671849-1 1996 BACKGROUND: Lithium, a drug frequently used for treatment of affective disorders, is known to cause a vasopressin-resistant state, leading to polyuria and polydipsia. Lithium 12-19 arginine vasopressin Rattus norvegicus 102-113 8671849-2 1996 It has been suggested that lithium interacts with the renal V2-vasopressin receptor. Lithium 27-34 arginine vasopressin Rattus norvegicus 63-74 7535800-2 1995 The effect of chronic lithium therapy on the expression of the vasopressin-regulated water channel Aquaporin-2 (AQP2) in rat kidney was examined. Lithium 22-29 arginine vasopressin Rattus norvegicus 63-74 10405197-10 1999 In Brattleboro rats or lithium-treated normal rats completely lacking vasopressin action, and hence having extremely low levels of AQP2 in the apical plasma membrane, AQP2 was undetectable in urine. Lithium 23-30 arginine vasopressin Rattus norvegicus 70-81 9406968-0 1997 Upregulation of the expression of vasopressin gene in the paraventricular and supraoptic nuclei of the lithium-induced diabetes insipidus rat. Lithium 103-110 arginine vasopressin Rattus norvegicus 34-45 9406968-1 1997 The expression of arginine vasopressin (AVP) gene in the paraventricular (PVN) and supraoptic nuclei (SON) was investigated in rats with lithium (Li)-induced polyuria, using in situ hybridization histochemistry and radioimmunoassay. Lithium 137-144 arginine vasopressin Rattus norvegicus 18-44 2373238-0 1990 Lithium potentiates vasopressin-, angiotensin II- and noradrenaline-induced DNA synthesis in rat hepatocytes. Lithium 0-7 arginine vasopressin Rattus norvegicus 20-32