PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21496400-2 2011 Besides myelin proteins, lipid components of CNS are supposed to play a role as antigens for T cells in MS. CD1 is a family of MHC-like glycoproteins specialized in capturing and presenting a variety of microbial and self lipids and glycolipids to antigen-specific T cells. Glycolipids 233-244 CD1a molecule Homo sapiens 108-111 21603161-1 2011 Group I CD1 (CD1a, CD1b, and CD1c) glycoproteins expressed on immature and mature dendritic cells present nonpeptide antigens (i.e., lipid or glycolipid molecules mainly of microbial origin) to T cells. Glycolipids 142-152 CD1a molecule Homo sapiens 13-17 15262497-2 2004 When iDCs were infected with HIV/VSV-G/+Nef, the surface expression of CD1a, a molecule for presenting glycolipid/lipid antigens, was selectively down-regulated among CD1 molecules (CD1a, -b, -c, and -d) as well as class I MHC. Glycolipids 103-113 CD1a molecule Homo sapiens 71-75 15723809-1 2005 CD1a is expressed on Langerhans cells (LCs) and dendritic cells (DCs), where it mediates T cell recognition of glycolipid and lipopeptide antigens that contain either one or two alkyl chains. Glycolipids 111-121 CD1a molecule Homo sapiens 0-4 17428545-1 2007 CD1 are MCH-like glycoproteins specialized in capturing and presenting glycolipid to T cells. Glycolipids 71-81 CD1a molecule Homo sapiens 0-3 15262497-2 2004 When iDCs were infected with HIV/VSV-G/+Nef, the surface expression of CD1a, a molecule for presenting glycolipid/lipid antigens, was selectively down-regulated among CD1 molecules (CD1a, -b, -c, and -d) as well as class I MHC. Glycolipids 103-113 CD1a molecule Homo sapiens 71-74 15262497-5 2004 These findings reveal that the HIV-1-Nef interferes with the intracellular trafficking of CD1a, and suggest the involvement of CD1a-restricted immune effectors in the protective immunity against HIV-1 infection, which implicates the feasibility of virus-derived glycolipid/lipid antigens together with epitope peptides for the vaccine development. Glycolipids 262-272 CD1a molecule Homo sapiens 127-131 14965307-1 2004 Although T cells were previously believed to recognize only peptide antigen associated with the major histocompatibility complex (MHC), recent studies have shown that there are unique T cells specialized for recognition of lipid or glycolipid antigens bound to the MHC class I-like CD1 molecules (CD1a, b, c or d). Glycolipids 232-242 CD1a molecule Homo sapiens 282-285 15187105-3 2004 CD1a, b, and c molecules present lipids or glycolipids to T cells and are involved in defense against microbial infections, especially mycobacteria. Glycolipids 43-54 CD1a molecule Homo sapiens 0-4 14965307-1 2004 Although T cells were previously believed to recognize only peptide antigen associated with the major histocompatibility complex (MHC), recent studies have shown that there are unique T cells specialized for recognition of lipid or glycolipid antigens bound to the MHC class I-like CD1 molecules (CD1a, b, c or d). Glycolipids 232-242 CD1a molecule Homo sapiens 297-301 12833155-1 2003 CD1 antigens bind a variety of self and foreign lipid and glycolipid antigens for presentation to CD1-restricted T cell receptors (TCRs). Glycolipids 58-68 CD1a molecule Homo sapiens 0-3 12833155-1 2003 CD1 antigens bind a variety of self and foreign lipid and glycolipid antigens for presentation to CD1-restricted T cell receptors (TCRs). Glycolipids 58-68 CD1a molecule Homo sapiens 98-101 12144626-1 2002 CD1 gene (CD1A to CD1E) products are involved in non-peptide antigen presentation, such as lipids and glycolipids, to T cells. Glycolipids 102-113 CD1a molecule Homo sapiens 0-3 12144626-1 2002 CD1 gene (CD1A to CD1E) products are involved in non-peptide antigen presentation, such as lipids and glycolipids, to T cells. Glycolipids 102-113 CD1a molecule Homo sapiens 10-14 11145856-2 2000 Human group 1 CD1 molecules (CD1a, CD1b, CD1c) are expressed mainly on professional antigen-presenting cells, and mediate presentation of microbial lipid and glycolipid antigens to T cells. Glycolipids 158-168 CD1a molecule Homo sapiens 29-33 11019917-1 2000 CD1 is a family of proteins structurally related to major histocompatibility complex (MHC) molecules and specialized in presenting lipids or glycolipids to T cells. Glycolipids 141-152 CD1a molecule Homo sapiens 0-3 10989309-1 2000 Glycolipid-specific, CD1a-, b- and c-dependent cytotoxic T cells have recently been shown to be involved in the host response against tuberculosis. Glycolipids 0-10 CD1a molecule Homo sapiens 21-25 11208113-5 2000 Thus, besides MHC class I and II, a third lineage of antigen-presenting molecules that bind lipid and glycolipid antigens rather than peptides exists and is mediated by the family of CD1 proteins. Glycolipids 102-112 CD1a molecule Homo sapiens 183-186 10890914-3 2000 In contrast, CD1a and CD1b molecules mediate the presentation of lipid and glycolipid antigens and differentially sample early recycling endosomes or late endocytic compartments, respectively, that contain distinct sets of lipid antigens. Glycolipids 75-85 CD1a molecule Homo sapiens 13-17 21258883-1 2011 CD1 molecules might contribute to anti-tumor immune response by presentation of tumor-derived lipid and glycolipid antigens to T cells and NKT cells. Glycolipids 104-114 CD1a molecule Homo sapiens 0-3 10395104-1 1999 CD1 molecules are able to present unusual antigens, lipids or glycolipids from mycobacterium cell walls to T lymphocytes. Glycolipids 62-73 CD1a molecule Homo sapiens 0-3 32467040-1 2020 CD1 glycoproteins are a class of antigen presenting molecules that bind and present non-peptidic antigens (lipids and glycolipids) for immune recognition. Glycolipids 118-129 CD1a molecule Homo sapiens 0-3 27156638-1 2016 CD1 molecules are specialized in capturing and presenting lipids and glycolipids to distinct subsets of T and NKT cells. Glycolipids 69-80 CD1a molecule Homo sapiens 0-3 10631954-2 1999 All four of the known human CD1 proteins (CD1a, CD1b, CD1c and CD1d) as well as murine CD1d have now been shown to mediate T-cell recognition of lipid or glycolipid antigens. Glycolipids 154-164 CD1a molecule Homo sapiens 42-46