PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7931322-0	1994	Phorbol ester- and retinoic acid-induced regulation of the protein kinase C substrate MARCKS in immortalized hippocampal cells.	Tretinoin	19-32	myristoylated alanine rich protein kinase C substrate	Homo sapiens	86-92	
7931322-1	1994	The expression of MARCKS, a major protein kinase C (PKC) substrate, was examined in the immortalized hippocampal cell line HN33, following differentiation using phorbol esters or retinoic acid.	Tretinoin	179-192	myristoylated alanine rich protein kinase C substrate	Homo sapiens	18-24	
7931322-7	1994	MARCKS protein expression was also down-regulated in a dose-dependent manner on exposure of HN33 cells to retinoic acid.	Tretinoin	106-119	myristoylated alanine rich protein kinase C substrate	Homo sapiens	0-6	
7931322-8	1994	In cells exposed to 10 microM retinoic acid, the MARCKS protein level was reduced in the membrane fraction within 4 h. Reduction of MARCKS protein levels was maximal (> 90%) by 12 h with no evidence for any alteration in PKC activity.	Tretinoin	30-43	myristoylated alanine rich protein kinase C substrate	Homo sapiens	49-55	
7931322-8	1994	In cells exposed to 10 microM retinoic acid, the MARCKS protein level was reduced in the membrane fraction within 4 h. Reduction of MARCKS protein levels was maximal (> 90%) by 12 h with no evidence for any alteration in PKC activity.	Tretinoin	30-43	myristoylated alanine rich protein kinase C substrate	Homo sapiens	132-138	
7931322-9	1994	Reduced levels of MARCKS protein were also observed in the soluble fraction of retinoic acid-exposed cells, but to a significantly lesser extent.	Tretinoin	79-92	myristoylated alanine rich protein kinase C substrate	Homo sapiens	18-24	
11115359-12	2000	In contrast, MARCKS increased in the membrane in response to retinoic acid treatment.	Tretinoin	61-74	myristoylated alanine rich protein kinase C substrate	Homo sapiens	13-19