PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31488317-8	2019	Furthermore, HCQ inhibited cell autophagy in breast cancer cells by regulating levels of p62, LC3-I and LC3-II.	Hydroxychloroquine	13-16	microtubule associated protein 1 light chain 3 alpha	Homo sapiens	94-97	
31488317-8	2019	Furthermore, HCQ inhibited cell autophagy in breast cancer cells by regulating levels of p62, LC3-I and LC3-II.	Hydroxychloroquine	13-16	microtubule associated protein 1 light chain 3 alpha	Homo sapiens	104-107	
29901098-8	2018	Notably, pharmacological blockade of autophagy activation using hydroxychloroquine markedly enhanced ART-induced apoptosis and increased the protein levels of cleaved caspase 3 and PARP, while decreasing the levels of LC3 and beclin-1.	Hydroxychloroquine	64-82	microtubule associated protein 1 light chain 3 alpha	Homo sapiens	218-221	
28382796-7	2017	Inhibition of autophagy protein LC3A using hydroxychloroquine (HCQ) increased sensitivity to cisplatin in CCC cells in vitro.	Hydroxychloroquine	43-61	microtubule associated protein 1 light chain 3 alpha	Homo sapiens	32-36	
28382796-7	2017	Inhibition of autophagy protein LC3A using hydroxychloroquine (HCQ) increased sensitivity to cisplatin in CCC cells in vitro.	Hydroxychloroquine	63-66	microtubule associated protein 1 light chain 3 alpha	Homo sapiens	32-36	
26211587-4	2015	The extent of cell death and features of HCQ-induced autophagic markers including increase in microtubule-associated protein light chain 3 (LC3) I conversion to LC3-II, beclin-1, ATG5, as well as green fluorescent protein-LC3 positive puncta and autophagosome were remarkably greater in U937/AR cells.	Hydroxychloroquine	41-44	microtubule associated protein 1 light chain 3 alpha	Homo sapiens	140-143	
26211587-4	2015	The extent of cell death and features of HCQ-induced autophagic markers including increase in microtubule-associated protein light chain 3 (LC3) I conversion to LC3-II, beclin-1, ATG5, as well as green fluorescent protein-LC3 positive puncta and autophagosome were remarkably greater in U937/AR cells.	Hydroxychloroquine	41-44	microtubule associated protein 1 light chain 3 alpha	Homo sapiens	161-164	
26211587-4	2015	The extent of cell death and features of HCQ-induced autophagic markers including increase in microtubule-associated protein light chain 3 (LC3) I conversion to LC3-II, beclin-1, ATG5, as well as green fluorescent protein-LC3 positive puncta and autophagosome were remarkably greater in U937/AR cells.	Hydroxychloroquine	41-44	microtubule associated protein 1 light chain 3 alpha	Homo sapiens	161-164	
26211587-8	2015	Knock down of p62/SQSTM1 using siRNA were prevented the HCQ-induced LC3-II protein level as well as significantly reduced the HCQ-induced cell death in U937/AR cells.	Hydroxychloroquine	56-59	microtubule associated protein 1 light chain 3 alpha	Homo sapiens	68-71	
24944668-8	2014	The results demonstrated that HCQ increased the expressions of LC3 mRNA and LC3II protein and GFP-LC3 signalling but reduced the expression of p62/STSQM1 in cervical cancer SiHa cells.	Hydroxychloroquine	30-33	microtubule associated protein 1 light chain 3 alpha	Homo sapiens	63-66	
24944668-8	2014	The results demonstrated that HCQ increased the expressions of LC3 mRNA and LC3II protein and GFP-LC3 signalling but reduced the expression of p62/STSQM1 in cervical cancer SiHa cells.	Hydroxychloroquine	30-33	microtubule associated protein 1 light chain 3 alpha	Homo sapiens	76-79	
23681079-3	2013	Recently, we have reported that immunohistochemistry for autophagic markers LC3 and p62 can replace electron microscopy in the diagnosis of HCQ-induced and colchicine-induced autophagic vacuolar skeletal myopathies.	Hydroxychloroquine	140-143	microtubule associated protein 1 light chain 3 alpha	Homo sapiens	76-79	
34217752-8	2021	The inhibition of SARS-CoV-2 replication by chloroquine and hydroxychloroquine coincided with an inhibitory effect on the autophagy pathway as visualized by a dose-dependent increase in LC3-positive puncta.	Hydroxychloroquine	60-78	microtubule associated protein 1 light chain 3 alpha	Homo sapiens	186-189	
35485606-4	2022	The expression of autophagy proteins (LC3A/B and Beclin-1) and UPS protein (ubiquitin) in MDA-MB-231 and MCF-7 cells following doxorubicin, ixazomib, and/or hydroxychloroquine were determined by western blot.	Hydroxychloroquine	157-175	microtubule associated protein 1 light chain 3 alpha	Homo sapiens	38-44