PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30603055-9 2018 Resected tumors from all nine HCQ-treated patients showed p62/sequestosome-1 induction indicative of autophagy-inhibition by HCQ. Hydroxychloroquine 30-33 sequestosome 1 Homo sapiens 58-61 30603055-9 2018 Resected tumors from all nine HCQ-treated patients showed p62/sequestosome-1 induction indicative of autophagy-inhibition by HCQ. Hydroxychloroquine 30-33 sequestosome 1 Homo sapiens 62-76 26211587-5 2015 Also, p62/SQSTM1 was increased in response to HCQ. Hydroxychloroquine 46-49 sequestosome 1 Homo sapiens 6-9 26211587-5 2015 Also, p62/SQSTM1 was increased in response to HCQ. Hydroxychloroquine 46-49 sequestosome 1 Homo sapiens 10-16 26211587-7 2015 Therefore, a reduction of p62/SQSTM1 indicates increased autophagic degradation, whereas an increase of p62/SQSTM1 by HCQ indicates inhibited autophagic degradation. Hydroxychloroquine 118-121 sequestosome 1 Homo sapiens 104-107 26211587-7 2015 Therefore, a reduction of p62/SQSTM1 indicates increased autophagic degradation, whereas an increase of p62/SQSTM1 by HCQ indicates inhibited autophagic degradation. Hydroxychloroquine 118-121 sequestosome 1 Homo sapiens 108-114 26211587-8 2015 Knock down of p62/SQSTM1 using siRNA were prevented the HCQ-induced LC3-II protein level as well as significantly reduced the HCQ-induced cell death in U937/AR cells. Hydroxychloroquine 56-59 sequestosome 1 Homo sapiens 14-17 26211587-8 2015 Knock down of p62/SQSTM1 using siRNA were prevented the HCQ-induced LC3-II protein level as well as significantly reduced the HCQ-induced cell death in U937/AR cells. Hydroxychloroquine 56-59 sequestosome 1 Homo sapiens 18-24 26211587-8 2015 Knock down of p62/SQSTM1 using siRNA were prevented the HCQ-induced LC3-II protein level as well as significantly reduced the HCQ-induced cell death in U937/AR cells. Hydroxychloroquine 126-129 sequestosome 1 Homo sapiens 14-17 26211587-8 2015 Knock down of p62/SQSTM1 using siRNA were prevented the HCQ-induced LC3-II protein level as well as significantly reduced the HCQ-induced cell death in U937/AR cells. Hydroxychloroquine 126-129 sequestosome 1 Homo sapiens 18-24 24944668-8 2014 The results demonstrated that HCQ increased the expressions of LC3 mRNA and LC3II protein and GFP-LC3 signalling but reduced the expression of p62/STSQM1 in cervical cancer SiHa cells. Hydroxychloroquine 30-33 sequestosome 1 Homo sapiens 143-146