PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33876698-0 2021 Binding of hydroxychloroquine and chloroquine dimers to palmitoyl-protein thioesterase 1 (PPT1) and its glycosylated forms: a computational approach. Hydroxychloroquine 11-29 palmitoyl-protein thioesterase 1 Homo sapiens 56-88 33876698-0 2021 Binding of hydroxychloroquine and chloroquine dimers to palmitoyl-protein thioesterase 1 (PPT1) and its glycosylated forms: a computational approach. Hydroxychloroquine 11-29 palmitoyl-protein thioesterase 1 Homo sapiens 90-94 33876698-4 2021 Potent and selective inhibitors of PPT1 have been designed, in particular 4-amino-7-chloro-quinoline derivatives such as hydroxychloroquine (HCQ) and the dimeric analogues Lys05 and DC661. Hydroxychloroquine 121-139 palmitoyl-protein thioesterase 1 Homo sapiens 35-39 33876698-4 2021 Potent and selective inhibitors of PPT1 have been designed, in particular 4-amino-7-chloro-quinoline derivatives such as hydroxychloroquine (HCQ) and the dimeric analogues Lys05 and DC661. Hydroxychloroquine 141-144 palmitoyl-protein thioesterase 1 Homo sapiens 35-39 30442709-4 2019 HCQ and Lys05 also bound to and inhibited PPT1 activity, but only DC661 maintained activity in acidic media. Hydroxychloroquine 0-3 palmitoyl-protein thioesterase 1 Homo sapiens 42-46