PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30797853-8 2019 However, this improvement was opposed by hydroxychloroquine induced autophagic inhibition as manifested by enhancing both LC3-II and P62 levels possibly through the prominent decline in sirtuin 1 level and elevated apoptotic biomarkers. Hydroxychloroquine 41-59 sirtuin 1 Rattus norvegicus 186-195