PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33160044-7 2021 RESULTS: The results suggested that HCQ in the treatment of RA was mainly associated with 4 targets that are smoothened homolog (SMO), sphingosine kinase (SPHK) 1, SPHK2 and gatty-acid amide hydrolase (FAAH), with their related 3276 proteins" network which regulate ErbB, HIF-1, NF-kappaB, FoxO, chemokines, MAPK, PI3K/Akt pathways and so forth. Hydroxychloroquine 36-39 smoothened, frizzled class receptor Homo sapiens 129-132 33160044-11 2021 SMO, SPHK1, SPHK2 and FAAH involving 3276 proteins become the multi-targets mechanism of HCQ in the treatment of RA. Hydroxychloroquine 89-92 smoothened, frizzled class receptor Homo sapiens 0-3