PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22626746-7 2012 In a multivariable analysis that adjusted for database source, maternal race/ethnicity, and anti-SSB/La status, HCQ use remained significantly associated with a decreased risk of cardiac-NL (odds ratio, 0.23; 95% confidence interval, 0.06-0.92; P=0.037). Hydroxychloroquine 112-115 small RNA binding exonuclease protection factor La Homo sapiens 97-100 20447951-0 2010 Evaluation of the risk of anti-SSA/Ro-SSB/La antibody-associated cardiac manifestations of neonatal lupus in fetuses of mothers with systemic lupus erythematosus exposed to hydroxychloroquine. Hydroxychloroquine 173-191 small RNA binding exonuclease protection factor La Homo sapiens 38-41 20447951-1 2010 BACKGROUND: Based on the potential involvement of Toll-like receptor (TLR) signalling in the pathogenesis of neonatal lupus (NL), it was hypothesised that fetal exposure to hydroxychloroquine (HCQ), a TLR inhibitor, might reduce the risk of anti-SSA/Ro/SSB/La antibody-associated cardiac manifestations of NL (cardiac-NL). Hydroxychloroquine 173-191 small RNA binding exonuclease protection factor La Homo sapiens 253-256 20447951-1 2010 BACKGROUND: Based on the potential involvement of Toll-like receptor (TLR) signalling in the pathogenesis of neonatal lupus (NL), it was hypothesised that fetal exposure to hydroxychloroquine (HCQ), a TLR inhibitor, might reduce the risk of anti-SSA/Ro/SSB/La antibody-associated cardiac manifestations of NL (cardiac-NL). Hydroxychloroquine 193-196 small RNA binding exonuclease protection factor La Homo sapiens 253-256 20447951-7 2010 CONCLUSION: This case-control study suggests that, in mothers with SLE with anti-SSA/Ro/SSB/La antibodies, exposure to HCQ during pregnancy may decrease the risk of fetal development of cardiac-NL. Hydroxychloroquine 119-122 small RNA binding exonuclease protection factor La Homo sapiens 88-91