PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29349515-11	2018	Interestingly, in hydroxychloroquine or topical corticosteroid-treated patients, MMP-2/-9 activity levels were found to be higher compared to untreated patients.	Hydroxychloroquine	18-36	matrix metallopeptidase 2	Homo sapiens	81-89	
34278709-0	2021	Attenuation of chloroquine and hydroxychloroquine on the invasive potential of bladder cancer through targeting matrix metalloproteinase 2 expression.	Hydroxychloroquine	31-49	matrix metallopeptidase 2	Homo sapiens	112-138	
34278709-4	2021	In this study, CQ and HCQ treatments inhibited the migration and invasion of two BC cell types (5637 and T24) through expression modulation of matrix metalloproteinase-2 (MMP-2), which belongs to the matrix MMP family and is a key mediator of cancer progression.	Hydroxychloroquine	22-25	matrix metallopeptidase 2	Homo sapiens	143-169	
34278709-4	2021	In this study, CQ and HCQ treatments inhibited the migration and invasion of two BC cell types (5637 and T24) through expression modulation of matrix metalloproteinase-2 (MMP-2), which belongs to the matrix MMP family and is a key mediator of cancer progression.	Hydroxychloroquine	22-25	matrix metallopeptidase 2	Homo sapiens	171-176	
34278709-4	2021	In this study, CQ and HCQ treatments inhibited the migration and invasion of two BC cell types (5637 and T24) through expression modulation of matrix metalloproteinase-2 (MMP-2), which belongs to the matrix MMP family and is a key mediator of cancer progression.	Hydroxychloroquine	22-25	matrix metallopeptidase 2	Homo sapiens	207-210	
34278709-6	2021	In conclusion, our research demonstrated that CQ and HCQ regulated cell motility in BC through MMP-2 downregulation by targeting autophagy functions, providing a novel therapeutic strategy for BC treatment.	Hydroxychloroquine	53-56	matrix metallopeptidase 2	Homo sapiens	95-100	
34182874-6	2021	METHODS: In this research, to explore the effect of HCQ for angiogenesis, we investigated: (1) Human umbilical vein endothelial cells (HUVECs) viability by CCK-8; (2) HUVECs migration by wound healing; (3) HUVEC angiogenesis by Matrigel assay in vitro; (4) mRNA expression of MMP-2 and VEGF by real-time quantitative Polymerase Chain Reaction (RT-PCR); (5) protein expression of VEGF, MMP-2 by western blot.	Hydroxychloroquine	52-55	matrix metallopeptidase 2	Homo sapiens	276-281	
34182874-6	2021	METHODS: In this research, to explore the effect of HCQ for angiogenesis, we investigated: (1) Human umbilical vein endothelial cells (HUVECs) viability by CCK-8; (2) HUVECs migration by wound healing; (3) HUVEC angiogenesis by Matrigel assay in vitro; (4) mRNA expression of MMP-2 and VEGF by real-time quantitative Polymerase Chain Reaction (RT-PCR); (5) protein expression of VEGF, MMP-2 by western blot.	Hydroxychloroquine	52-55	matrix metallopeptidase 2	Homo sapiens	385-390	
34182874-7	2021	RESULTS: We found that HCQ treatment significantly restored the expression of aPL-inhibited VEGF and MMP-2.	Hydroxychloroquine	23-26	matrix metallopeptidase 2	Homo sapiens	101-106