PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20930627-2 2010 Expanded insights into the site-specific expression of the GSTs in defined parts of the nephron during renal damage are presented, with particular emphasis on the pathogenesis of cardiac surgery and cardiopulmonary bypass (CPB)-associated AKI and the role of GSTs in oxygen radical disposal. Reactive Oxygen Species 267-281 glutathione S-transferase kappa 1 Homo sapiens 59-63 22392772-2 2012 Glutathione (GSH) fulfills a universal role as redox factor, scavenger of reactive oxygen species, and as an essential substrate in the conjugation, detoxification, and reduction reactions catalyzed by glutathione S-transferase (GST). Reactive Oxygen Species 74-97 glutathione S-transferase kappa 1 Homo sapiens 202-227 21771003-2 2011 Defence against reactive oxygen species in the skin involves a variety of antioxidant enzymes, including glutathione-S-transferases (GSTs) catalysing the reaction between reduced glutathione, and a variety of exogenously and endogenously derived electrophilic compounds. Reactive Oxygen Species 16-39 glutathione S-transferase kappa 1 Homo sapiens 105-131 21771003-2 2011 Defence against reactive oxygen species in the skin involves a variety of antioxidant enzymes, including glutathione-S-transferases (GSTs) catalysing the reaction between reduced glutathione, and a variety of exogenously and endogenously derived electrophilic compounds. Reactive Oxygen Species 16-39 glutathione S-transferase kappa 1 Homo sapiens 133-137 25657676-2 2012 Glutathione S-transferase (GST) acting with other antioxidant enzymes can eliminate reactive oxygen species and protect cells against oxidative damage. Reactive Oxygen Species 84-107 glutathione S-transferase kappa 1 Homo sapiens 0-25 25657676-2 2012 Glutathione S-transferase (GST) acting with other antioxidant enzymes can eliminate reactive oxygen species and protect cells against oxidative damage. Reactive Oxygen Species 84-107 glutathione S-transferase kappa 1 Homo sapiens 27-30 20074657-2 2010 The glutathione-S-transferase (GST) isoenzymes detoxify the reactive oxygen species generated by chemotherapy agents and radiation. Reactive Oxygen Species 60-83 glutathione S-transferase kappa 1 Homo sapiens 4-29 20074657-2 2010 The glutathione-S-transferase (GST) isoenzymes detoxify the reactive oxygen species generated by chemotherapy agents and radiation. Reactive Oxygen Species 60-83 glutathione S-transferase kappa 1 Homo sapiens 31-34 19650429-5 2009 The redox status of the cell is maintained by antioxidant enzymes such as superoxide dismuthase, catalase, glutathione S-transferase and other substances such as glutathione, vitamins E, C and A, which provide to eliminate ROS. Reactive Oxygen Species 223-226 glutathione S-transferase kappa 1 Homo sapiens 107-132 19782926-2 2009 Glutathione S-transferase (GST) enzyme is involved in detoxification of reactive oxygen species. Reactive Oxygen Species 72-95 glutathione S-transferase kappa 1 Homo sapiens 0-25 19782926-2 2009 Glutathione S-transferase (GST) enzyme is involved in detoxification of reactive oxygen species. Reactive Oxygen Species 72-95 glutathione S-transferase kappa 1 Homo sapiens 27-30 21462720-5 2010 The combined toxicity was then confirmed as ROS associated oxidative stress with up to 300% and 35% increase of the intracellular ROS level and glutathione S-transferase (GST) activity, respectively. Reactive Oxygen Species 44-47 glutathione S-transferase kappa 1 Homo sapiens 144-169 21462720-5 2010 The combined toxicity was then confirmed as ROS associated oxidative stress with up to 300% and 35% increase of the intracellular ROS level and glutathione S-transferase (GST) activity, respectively. Reactive Oxygen Species 44-47 glutathione S-transferase kappa 1 Homo sapiens 171-174 21462720-7 2010 Therefore, the ROS associated oxidant injury might be responsible for the QDs-Cu2+/CU2+ induced toxicity and could be balanced through cytoprotective antioxidant enzyme GST. Reactive Oxygen Species 15-18 glutathione S-transferase kappa 1 Homo sapiens 169-172 18288203-3 2008 Experimental evidence supports a role for reactive oxygen species (ROS) in the pathogenesis of PLE, and the family of glutathione-S-transferase (GST) enzymes exerts a critical physiological role in cellular protection against this oxidative damage. Reactive Oxygen Species 42-65 glutathione S-transferase kappa 1 Homo sapiens 145-148 19842992-1 2009 BACKGROUND: Glutathione S-transferase (GST) enzymes are critical for detoxifying reactive oxygen species (ROS) and their products which have been implicated in the pathology of inflammatory diseases such as atopic dermatitis (AD). Reactive Oxygen Species 81-104 glutathione S-transferase kappa 1 Homo sapiens 12-37 19842992-1 2009 BACKGROUND: Glutathione S-transferase (GST) enzymes are critical for detoxifying reactive oxygen species (ROS) and their products which have been implicated in the pathology of inflammatory diseases such as atopic dermatitis (AD). Reactive Oxygen Species 81-104 glutathione S-transferase kappa 1 Homo sapiens 39-42 19842992-1 2009 BACKGROUND: Glutathione S-transferase (GST) enzymes are critical for detoxifying reactive oxygen species (ROS) and their products which have been implicated in the pathology of inflammatory diseases such as atopic dermatitis (AD). Reactive Oxygen Species 106-109 glutathione S-transferase kappa 1 Homo sapiens 12-37 19842992-1 2009 BACKGROUND: Glutathione S-transferase (GST) enzymes are critical for detoxifying reactive oxygen species (ROS) and their products which have been implicated in the pathology of inflammatory diseases such as atopic dermatitis (AD). Reactive Oxygen Species 106-109 glutathione S-transferase kappa 1 Homo sapiens 39-42 16409207-3 2006 Members of the glutathione-S-transferase (GST) superfamily of genes are important in protection of cells from reactive oxygen species. Reactive Oxygen Species 110-133 glutathione S-transferase kappa 1 Homo sapiens 15-40 32689267-5 2006 Salicylic acid biosynthesis and expression of several defence genes including PR-1 and glutathione-S-transferase, which are involved in ethylene and reactive oxygen species dependent signalling, were highly up-regulated in upper-uninoculated (systemic) leaves of PVX-infected potato plants compared with mock-inoculated controls. Reactive Oxygen Species 149-172 glutathione S-transferase kappa 1 Homo sapiens 87-112 17619555-1 2007 Glutathione S-transferases (GSTs) constitute a super family of dimeric phase II metabolic enzymes that catalyze the conjugation of reduced glutathione with various electrophilic compounds and reactive oxygen species (ROS). Reactive Oxygen Species 192-215 glutathione S-transferase kappa 1 Homo sapiens 0-26 17619555-1 2007 Glutathione S-transferases (GSTs) constitute a super family of dimeric phase II metabolic enzymes that catalyze the conjugation of reduced glutathione with various electrophilic compounds and reactive oxygen species (ROS). Reactive Oxygen Species 192-215 glutathione S-transferase kappa 1 Homo sapiens 28-32 17619555-1 2007 Glutathione S-transferases (GSTs) constitute a super family of dimeric phase II metabolic enzymes that catalyze the conjugation of reduced glutathione with various electrophilic compounds and reactive oxygen species (ROS). Reactive Oxygen Species 217-220 glutathione S-transferase kappa 1 Homo sapiens 0-26 17619555-1 2007 Glutathione S-transferases (GSTs) constitute a super family of dimeric phase II metabolic enzymes that catalyze the conjugation of reduced glutathione with various electrophilic compounds and reactive oxygen species (ROS). Reactive Oxygen Species 217-220 glutathione S-transferase kappa 1 Homo sapiens 28-32 18067039-1 2007 BACKGROUND AND OBJECTIVE: Glutathione-S-transferase (GST) is the superfamily of genes that provides protection to the cells against reactive oxygen species and plays a vital role in phase II of biotransformation of many substances. Reactive Oxygen Species 132-155 glutathione S-transferase kappa 1 Homo sapiens 26-51 18067039-1 2007 BACKGROUND AND OBJECTIVE: Glutathione-S-transferase (GST) is the superfamily of genes that provides protection to the cells against reactive oxygen species and plays a vital role in phase II of biotransformation of many substances. Reactive Oxygen Species 132-155 glutathione S-transferase kappa 1 Homo sapiens 53-56 16328000-1 2006 Glutathione S-transferase (GST) enzymes catalyse the detoxification of by-products of reactive oxygen species and are thus important in cellular defence mechanisms. Reactive Oxygen Species 86-109 glutathione S-transferase kappa 1 Homo sapiens 0-25 16328000-1 2006 Glutathione S-transferase (GST) enzymes catalyse the detoxification of by-products of reactive oxygen species and are thus important in cellular defence mechanisms. Reactive Oxygen Species 86-109 glutathione S-transferase kappa 1 Homo sapiens 27-30 16409207-3 2006 Members of the glutathione-S-transferase (GST) superfamily of genes are important in protection of cells from reactive oxygen species. Reactive Oxygen Species 110-133 glutathione S-transferase kappa 1 Homo sapiens 42-45 16340710-7 2005 Because the formation of reactive oxygen species is a major aspect of the inflammatory process of asthma, genetic aberrations associated with antioxidants such as glutathione S-transferase (GST) may shed light on reasons why some people with asthma seem more at risk of exacerbations as a result of air pollution. Reactive Oxygen Species 25-48 glutathione S-transferase kappa 1 Homo sapiens 190-193 16049007-10 2005 Furthermore, H(2)O(2) treatment not only induced GST expression but also increased intracellular maspin/GST interaction, which was inversely correlated with the level of ROS generation. Reactive Oxygen Species 170-173 glutathione S-transferase kappa 1 Homo sapiens 104-107 16049007-12 2005 Furthermore, the maspin effect on ROS generation was completely abolished by a GST inhibitor, indicating an essential role of GST in maspin-mediated cellular response to oxidative stress. Reactive Oxygen Species 34-37 glutathione S-transferase kappa 1 Homo sapiens 79-82 16049007-12 2005 Furthermore, the maspin effect on ROS generation was completely abolished by a GST inhibitor, indicating an essential role of GST in maspin-mediated cellular response to oxidative stress. Reactive Oxygen Species 34-37 glutathione S-transferase kappa 1 Homo sapiens 126-129 16049007-14 2005 Together, our data suggest a new mechanism by which maspin, through its direct interaction with GST, may inhibit oxidative stress-induced ROS generation and vascular endothelial growth factor A induction, thus preventing further adverse effects on tumor genetics and stromal reactivity. Reactive Oxygen Species 138-141 glutathione S-transferase kappa 1 Homo sapiens 96-99 12883385-1 2003 Glutathione-S-transferase (GST) genes encode a family of detoxification enzymes that offer protection against endogenous and exogenous sources of reactive oxygen species (ROS). Reactive Oxygen Species 146-169 glutathione S-transferase kappa 1 Homo sapiens 0-25 15375523-1 2004 Glutathione S-transferase (GST) is known to play a key role in the detoxification and reduction of reactive oxygen species (ROS). Reactive Oxygen Species 99-122 glutathione S-transferase kappa 1 Homo sapiens 0-25 15375523-1 2004 Glutathione S-transferase (GST) is known to play a key role in the detoxification and reduction of reactive oxygen species (ROS). Reactive Oxygen Species 99-122 glutathione S-transferase kappa 1 Homo sapiens 27-30 15375523-1 2004 Glutathione S-transferase (GST) is known to play a key role in the detoxification and reduction of reactive oxygen species (ROS). Reactive Oxygen Species 124-127 glutathione S-transferase kappa 1 Homo sapiens 0-25 15375523-1 2004 Glutathione S-transferase (GST) is known to play a key role in the detoxification and reduction of reactive oxygen species (ROS). Reactive Oxygen Species 124-127 glutathione S-transferase kappa 1 Homo sapiens 27-30 15934438-2 2005 Glutathione S-transferase (GST) is involved in the detoxification of ROS and genetic polymorphisms of GSTM1, GSTT1 and GSTP1 are associated with altered enzyme activity. Reactive Oxygen Species 69-72 glutathione S-transferase kappa 1 Homo sapiens 0-25 15934438-2 2005 Glutathione S-transferase (GST) is involved in the detoxification of ROS and genetic polymorphisms of GSTM1, GSTT1 and GSTP1 are associated with altered enzyme activity. Reactive Oxygen Species 69-72 glutathione S-transferase kappa 1 Homo sapiens 27-30 12883385-1 2003 Glutathione-S-transferase (GST) genes encode a family of detoxification enzymes that offer protection against endogenous and exogenous sources of reactive oxygen species (ROS). Reactive Oxygen Species 146-169 glutathione S-transferase kappa 1 Homo sapiens 27-30 12883385-1 2003 Glutathione-S-transferase (GST) genes encode a family of detoxification enzymes that offer protection against endogenous and exogenous sources of reactive oxygen species (ROS). Reactive Oxygen Species 171-174 glutathione S-transferase kappa 1 Homo sapiens 0-25 12883385-1 2003 Glutathione-S-transferase (GST) genes encode a family of detoxification enzymes that offer protection against endogenous and exogenous sources of reactive oxygen species (ROS). Reactive Oxygen Species 171-174 glutathione S-transferase kappa 1 Homo sapiens 27-30 12883385-2 2003 Germline variations in GST genes may alter the catalytic efficiency of GST isoenzymes leading to a potential increase in susceptibility to the genotoxic effects of ROS and electrophilic substances. Reactive Oxygen Species 164-167 glutathione S-transferase kappa 1 Homo sapiens 23-26 12883385-2 2003 Germline variations in GST genes may alter the catalytic efficiency of GST isoenzymes leading to a potential increase in susceptibility to the genotoxic effects of ROS and electrophilic substances. Reactive Oxygen Species 164-167 glutathione S-transferase kappa 1 Homo sapiens 71-74 11044240-3 2000 The glutathione S-transferase enzymes play a major role in limiting the toxic effects of reactive oxygen species, and this study was designed to determine whether polymorphisms in these enzymes are associated with skin cancers in renal transplant recipients. Reactive Oxygen Species 89-112 glutathione S-transferase kappa 1 Homo sapiens 4-29 12563680-2 2003 The glutathione S-transferase (GST) genes GSTM1, GSTT1, and GSTP1 catalyze metabolic pathways for the excretion of reactive oxygen species that may be generated by cellular oxidative stress induced by ultraviolet radiation in sunlight. Reactive Oxygen Species 115-138 glutathione S-transferase kappa 1 Homo sapiens 4-29 12563680-2 2003 The glutathione S-transferase (GST) genes GSTM1, GSTT1, and GSTP1 catalyze metabolic pathways for the excretion of reactive oxygen species that may be generated by cellular oxidative stress induced by ultraviolet radiation in sunlight. Reactive Oxygen Species 115-138 glutathione S-transferase kappa 1 Homo sapiens 31-34 7819227-3 1995 To study the role of reactive oxygen species in the induction of AP-1 activity and GST Ya gene expression and their effect on intracellular GSH levels, we have exposed hepatoma cells to adriamycin and two synthetic quinones, Qcb and Qn, with different capacities to generate oxygen radicals. Reactive Oxygen Species 21-44 glutathione S-transferase kappa 1 Homo sapiens 83-86 9630012-4 1998 Glutathione S-transferase (GST) activity was measured as it may be affected by oxygen radicals. Reactive Oxygen Species 79-94 glutathione S-transferase kappa 1 Homo sapiens 0-25 9630012-4 1998 Glutathione S-transferase (GST) activity was measured as it may be affected by oxygen radicals. Reactive Oxygen Species 79-94 glutathione S-transferase kappa 1 Homo sapiens 27-30 10783335-2 2000 Recent data have pointed to interactions of the FANCC protein (encoded by the FA complementation group C gene, FA-C) with NADPH cytochrome P450 reductase and glutathione S-transferase (GST), two activities involved in either triggering or detoxifying reactive intermediates, including xenobiotics and reactive oxygen species. Reactive Oxygen Species 301-324 glutathione S-transferase kappa 1 Homo sapiens 158-183 10783335-2 2000 Recent data have pointed to interactions of the FANCC protein (encoded by the FA complementation group C gene, FA-C) with NADPH cytochrome P450 reductase and glutathione S-transferase (GST), two activities involved in either triggering or detoxifying reactive intermediates, including xenobiotics and reactive oxygen species. Reactive Oxygen Species 301-324 glutathione S-transferase kappa 1 Homo sapiens 185-188 10557101-4 1999 The mechanisms, which underlie the ROS-mediated response, involve direct alteration of kinases and transcription factors, and indirect modulation of cysteine-rich redox-sensitive proteins exemplified by thioredoxin and glutathione S-transferase. Reactive Oxygen Species 35-38 glutathione S-transferase kappa 1 Homo sapiens 219-244 7819227-6 1995 Furthermore, we show that the induction of AP-1 binding activity and GST Ya gene expression by these quinones correlates with their oxygen radical production, adriamycin and Qcb being stronger inducers that Qn. Reactive Oxygen Species 132-146 glutathione S-transferase kappa 1 Homo sapiens 69-72 8261458-6 1994 These findings suggest that diverse chemicals that induce the AP-1 complex, leading to the AP-1-mediated transcriptional activation of glutathione S-transferase Ya gene expression, may act through a common mechanism involving the production of reactive oxygen species and depletion of reduced glutathione. Reactive Oxygen Species 244-267 glutathione S-transferase kappa 1 Homo sapiens 135-160 8770536-13 1995 It also appears probable that GST are regulated in vivo by reactive oxygen species (ROS), because not only are some of the most potent inducers capable of generating free radicals by redox-cycling, but H2O2 has been shown to induce GST in plant and mammalian cells: induction of GST by ROS would appear to represent an adaptive response as these enzymes detoxify some of the toxic carbonyl-, peroxide-, and epoxide-containing metabolites produced within the cell by oxidative stress. Reactive Oxygen Species 59-82 glutathione S-transferase kappa 1 Homo sapiens 30-33 8770536-13 1995 It also appears probable that GST are regulated in vivo by reactive oxygen species (ROS), because not only are some of the most potent inducers capable of generating free radicals by redox-cycling, but H2O2 has been shown to induce GST in plant and mammalian cells: induction of GST by ROS would appear to represent an adaptive response as these enzymes detoxify some of the toxic carbonyl-, peroxide-, and epoxide-containing metabolites produced within the cell by oxidative stress. Reactive Oxygen Species 59-82 glutathione S-transferase kappa 1 Homo sapiens 232-235 8770536-13 1995 It also appears probable that GST are regulated in vivo by reactive oxygen species (ROS), because not only are some of the most potent inducers capable of generating free radicals by redox-cycling, but H2O2 has been shown to induce GST in plant and mammalian cells: induction of GST by ROS would appear to represent an adaptive response as these enzymes detoxify some of the toxic carbonyl-, peroxide-, and epoxide-containing metabolites produced within the cell by oxidative stress. Reactive Oxygen Species 59-82 glutathione S-transferase kappa 1 Homo sapiens 232-235 8770536-13 1995 It also appears probable that GST are regulated in vivo by reactive oxygen species (ROS), because not only are some of the most potent inducers capable of generating free radicals by redox-cycling, but H2O2 has been shown to induce GST in plant and mammalian cells: induction of GST by ROS would appear to represent an adaptive response as these enzymes detoxify some of the toxic carbonyl-, peroxide-, and epoxide-containing metabolites produced within the cell by oxidative stress. Reactive Oxygen Species 84-87 glutathione S-transferase kappa 1 Homo sapiens 30-33 8770536-13 1995 It also appears probable that GST are regulated in vivo by reactive oxygen species (ROS), because not only are some of the most potent inducers capable of generating free radicals by redox-cycling, but H2O2 has been shown to induce GST in plant and mammalian cells: induction of GST by ROS would appear to represent an adaptive response as these enzymes detoxify some of the toxic carbonyl-, peroxide-, and epoxide-containing metabolites produced within the cell by oxidative stress. Reactive Oxygen Species 84-87 glutathione S-transferase kappa 1 Homo sapiens 232-235 8770536-13 1995 It also appears probable that GST are regulated in vivo by reactive oxygen species (ROS), because not only are some of the most potent inducers capable of generating free radicals by redox-cycling, but H2O2 has been shown to induce GST in plant and mammalian cells: induction of GST by ROS would appear to represent an adaptive response as these enzymes detoxify some of the toxic carbonyl-, peroxide-, and epoxide-containing metabolites produced within the cell by oxidative stress. Reactive Oxygen Species 84-87 glutathione S-transferase kappa 1 Homo sapiens 232-235 8770536-13 1995 It also appears probable that GST are regulated in vivo by reactive oxygen species (ROS), because not only are some of the most potent inducers capable of generating free radicals by redox-cycling, but H2O2 has been shown to induce GST in plant and mammalian cells: induction of GST by ROS would appear to represent an adaptive response as these enzymes detoxify some of the toxic carbonyl-, peroxide-, and epoxide-containing metabolites produced within the cell by oxidative stress. Reactive Oxygen Species 286-289 glutathione S-transferase kappa 1 Homo sapiens 30-33 23932298-3 2013 The safe elimination of reactive oxygen species and toxins via glutathione S-transferase (GST) pathways is required in order to protect cells against reactive oxygen-induced damage. Reactive Oxygen Species 24-47 glutathione S-transferase kappa 1 Homo sapiens 63-88 23932298-3 2013 The safe elimination of reactive oxygen species and toxins via glutathione S-transferase (GST) pathways is required in order to protect cells against reactive oxygen-induced damage. Reactive Oxygen Species 24-47 glutathione S-transferase kappa 1 Homo sapiens 90-93 32712936-1 2020 Antioxidant enzymes such as glutathione S-transferases (GSTs) and cytochromes P450 (CYPs) are involved in the metabolism and detoxification of cytotoxic compounds, as well as the elimination of reactive oxygen species (ROS). Reactive Oxygen Species 194-217 glutathione S-transferase kappa 1 Homo sapiens 28-54 34198827-8 2021 Taken together, these results indicate that carnosic acid could down-regulate ROS level in an early stage of MPI-induced adipocyte differentiation by attenuating ROS generation through suppression of NF-kappaB-mediated translation of Nox4 enzyme and increasing ROS neutralization through induction of Nrf2-mediated translation of phase II antioxidant enzymes such as HO-1, gamma-GCS, and GST, leading to its anti-adipogenetic effect. Reactive Oxygen Species 78-81 glutathione S-transferase kappa 1 Homo sapiens 388-391 2488988-1 1989 This review focuses on parasite enzymes which are involved in the detoxification of oxygen radicals, and covers the following enzymes: superoxide dismutase, catalase, glutathione peroxidase, glutathione-S-transferase and glutathione reductase. Reactive Oxygen Species 84-99 glutathione S-transferase kappa 1 Homo sapiens 191-216 33972602-7 2021 GSTM1, encoding a glutathione S-transferase that metabolizes reactive oxygen species and xenobiotics, is upregulated. Reactive Oxygen Species 61-84 glutathione S-transferase kappa 1 Homo sapiens 18-43 33960160-11 2021 DISCUSSION: Glutathione-S-transferase (GSTP1) is a multifunctional protein that protects sperm cells from the damaging effects of reactive oxygen species and xenobiotics. Reactive Oxygen Species 130-153 glutathione S-transferase kappa 1 Homo sapiens 12-37 32712936-1 2020 Antioxidant enzymes such as glutathione S-transferases (GSTs) and cytochromes P450 (CYPs) are involved in the metabolism and detoxification of cytotoxic compounds, as well as the elimination of reactive oxygen species (ROS). Reactive Oxygen Species 194-217 glutathione S-transferase kappa 1 Homo sapiens 56-60 32712936-1 2020 Antioxidant enzymes such as glutathione S-transferases (GSTs) and cytochromes P450 (CYPs) are involved in the metabolism and detoxification of cytotoxic compounds, as well as the elimination of reactive oxygen species (ROS). Reactive Oxygen Species 219-222 glutathione S-transferase kappa 1 Homo sapiens 28-54 32712936-1 2020 Antioxidant enzymes such as glutathione S-transferases (GSTs) and cytochromes P450 (CYPs) are involved in the metabolism and detoxification of cytotoxic compounds, as well as the elimination of reactive oxygen species (ROS). Reactive Oxygen Species 219-222 glutathione S-transferase kappa 1 Homo sapiens 56-60 31452310-4 2019 The GSTs belong to a major group of detoxification enzymes involved in the detoxification metabolism responsible for the protection of cells against reactive oxygen species (ROS) or electrophiles. Reactive Oxygen Species 149-172 glutathione S-transferase kappa 1 Homo sapiens 4-8 33228528-6 2020 To scavenge the ROS, the Badila genotype illustrated a substantial enhancement of antioxidants i.e. glutathione s-transferase (GST), as compared to its resistant counterpart. Reactive Oxygen Species 16-19 glutathione S-transferase kappa 1 Homo sapiens 100-125 31452310-4 2019 The GSTs belong to a major group of detoxification enzymes involved in the detoxification metabolism responsible for the protection of cells against reactive oxygen species (ROS) or electrophiles. Reactive Oxygen Species 174-177 glutathione S-transferase kappa 1 Homo sapiens 4-8 27021019-5 2017 The glutathione S-transferases (GSTs) are critical for the protection of cells from ROS. Reactive Oxygen Species 84-87 glutathione S-transferase kappa 1 Homo sapiens 32-36 30176726-8 2018 In addition, genes encoding cathepsin and GST and genes related to inducing reactive oxygen species (ROS) were all upregulated, which highly probably linked with degrading microcystin in flagellates. Reactive Oxygen Species 76-99 glutathione S-transferase kappa 1 Homo sapiens 42-45 30176726-8 2018 In addition, genes encoding cathepsin and GST and genes related to inducing reactive oxygen species (ROS) were all upregulated, which highly probably linked with degrading microcystin in flagellates. Reactive Oxygen Species 101-104 glutathione S-transferase kappa 1 Homo sapiens 42-45 29875076-1 2018 Glutathione S Transferases (GST) are anti-oxidant enzymes involved in detoxification of cellular and exogenous carcinogens and oxidative products of reactive oxygen species. Reactive Oxygen Species 149-172 glutathione S-transferase kappa 1 Homo sapiens 0-26 29875076-1 2018 Glutathione S Transferases (GST) are anti-oxidant enzymes involved in detoxification of cellular and exogenous carcinogens and oxidative products of reactive oxygen species. Reactive Oxygen Species 149-172 glutathione S-transferase kappa 1 Homo sapiens 28-31 31092607-0 2019 Contraction of the ROS Scavenging Enzyme Glutathione S-Transferase Gene Family in Cetaceans. Reactive Oxygen Species 19-22 glutathione S-transferase kappa 1 Homo sapiens 41-66 29505746-1 2018 N-acetyltransferase-2 (NAT2) and Glutathione S-transferases (GSTs) are phase-II xenobiotic metabolizing enzymes participating in detoxification of toxic arylamines, aromatic amines, hydrazines and reactive oxygen species (ROS), which are produced under oxidative and electrophile stresses. Reactive Oxygen Species 197-220 glutathione S-transferase kappa 1 Homo sapiens 61-65 29505746-1 2018 N-acetyltransferase-2 (NAT2) and Glutathione S-transferases (GSTs) are phase-II xenobiotic metabolizing enzymes participating in detoxification of toxic arylamines, aromatic amines, hydrazines and reactive oxygen species (ROS), which are produced under oxidative and electrophile stresses. Reactive Oxygen Species 222-225 glutathione S-transferase kappa 1 Homo sapiens 61-65 27458849-1 2016 BACKGROUND/AIMS: Glutathione and glutathione S-transferases (GST) are involved in cell defence against reactive oxygen species, which induces oxidative stress and are associated with different chronic diseases. Reactive Oxygen Species 103-126 glutathione S-transferase kappa 1 Homo sapiens 33-59 27458849-1 2016 BACKGROUND/AIMS: Glutathione and glutathione S-transferases (GST) are involved in cell defence against reactive oxygen species, which induces oxidative stress and are associated with different chronic diseases. Reactive Oxygen Species 103-126 glutathione S-transferase kappa 1 Homo sapiens 61-64 27377684-2 2016 Glutathione-S-transferase (GST) is primarily involved in the neutralization of reactive oxygen species (ROS) by enzymatic conjugation with the scavenger peptide glutathione (GSH). Reactive Oxygen Species 79-102 glutathione S-transferase kappa 1 Homo sapiens 0-25 27005784-8 2016 Reduced levels of GSH and GST indicate that there is a higher level of reactive oxygen species inducing oxidative stress in the body. Reactive Oxygen Species 71-94 glutathione S-transferase kappa 1 Homo sapiens 26-29 27377684-2 2016 Glutathione-S-transferase (GST) is primarily involved in the neutralization of reactive oxygen species (ROS) by enzymatic conjugation with the scavenger peptide glutathione (GSH). Reactive Oxygen Species 79-102 glutathione S-transferase kappa 1 Homo sapiens 27-30 27377684-2 2016 Glutathione-S-transferase (GST) is primarily involved in the neutralization of reactive oxygen species (ROS) by enzymatic conjugation with the scavenger peptide glutathione (GSH). Reactive Oxygen Species 104-107 glutathione S-transferase kappa 1 Homo sapiens 0-25 27377684-2 2016 Glutathione-S-transferase (GST) is primarily involved in the neutralization of reactive oxygen species (ROS) by enzymatic conjugation with the scavenger peptide glutathione (GSH). Reactive Oxygen Species 104-107 glutathione S-transferase kappa 1 Homo sapiens 27-30 25729577-7 2015 Specific inhibitors of the antioxidant enzymes, superoxide dismutase 1, glutathione S-transferase, and thioredoxin reductase, but not catalase, enhanced jadomycin-mediated ROS generation and anticancer activity. Reactive Oxygen Species 172-175 glutathione S-transferase kappa 1 Homo sapiens 72-97 24667798-13 2014 There was marked decrease in the level of GSH and activity of Glutathione reductase and glutathione-s-transferase leading to increased generation of reactive oxygen species. Reactive Oxygen Species 149-172 glutathione S-transferase kappa 1 Homo sapiens 88-113 25186055-1 2014 Glutathione S-transferases (GSTs) are important in the detoxification of many compounds, including reactive oxygen species. Reactive Oxygen Species 99-122 glutathione S-transferase kappa 1 Homo sapiens 0-26 25186055-1 2014 Glutathione S-transferases (GSTs) are important in the detoxification of many compounds, including reactive oxygen species. Reactive Oxygen Species 99-122 glutathione S-transferase kappa 1 Homo sapiens 28-32 25323504-3 2015 In this regard, GSH present in the cells works by neutralizing ROS and other xenobiotics through the glutathione S-transferase (GST) enzyme. Reactive Oxygen Species 63-66 glutathione S-transferase kappa 1 Homo sapiens 101-126 25323504-3 2015 In this regard, GSH present in the cells works by neutralizing ROS and other xenobiotics through the glutathione S-transferase (GST) enzyme. Reactive Oxygen Species 63-66 glutathione S-transferase kappa 1 Homo sapiens 128-131 25323504-5 2015 Therefore, the detection of GST levels is fundamental in the clinical diagnosis of ROS-related diseases. Reactive Oxygen Species 83-86 glutathione S-transferase kappa 1 Homo sapiens 28-31 24949025-2 2014 Glutathione S-transferase (GST) enzyme is involved in detoxification of reactive oxygen species. Reactive Oxygen Species 72-95 glutathione S-transferase kappa 1 Homo sapiens 0-25 24949025-2 2014 Glutathione S-transferase (GST) enzyme is involved in detoxification of reactive oxygen species. Reactive Oxygen Species 72-95 glutathione S-transferase kappa 1 Homo sapiens 27-30 25258576-3 2014 Proteins of the GST family (glutathione S-transferases) are enzymes detoxifying a wide range of hazardous substances, such as reactive oxygen species (ROS) or xenobionts. Reactive Oxygen Species 126-149 glutathione S-transferase kappa 1 Homo sapiens 16-19 24407598-1 2014 Glutathione S-transferases (GSTs) carry out a wide range of functions in cells, such as detoxification of endogenous compounds, removal of reactive oxygen species, and even catalysis of reactions in metabolic pathways beyond detoxification. Reactive Oxygen Species 139-162 glutathione S-transferase kappa 1 Homo sapiens 0-26 24407598-1 2014 Glutathione S-transferases (GSTs) carry out a wide range of functions in cells, such as detoxification of endogenous compounds, removal of reactive oxygen species, and even catalysis of reactions in metabolic pathways beyond detoxification. Reactive Oxygen Species 139-162 glutathione S-transferase kappa 1 Homo sapiens 28-32 25258576-3 2014 Proteins of the GST family (glutathione S-transferases) are enzymes detoxifying a wide range of hazardous substances, such as reactive oxygen species (ROS) or xenobionts. Reactive Oxygen Species 151-154 glutathione S-transferase kappa 1 Homo sapiens 16-19 23537991-1 2013 The glutathione S-transferases (GSTs) are a family of phase II xenobiotic metabolizing enzymes known to be involved in the detoxification and elimination of reactive oxygen species (ROS), thus defending tissues against oxidative stress. Reactive Oxygen Species 157-180 glutathione S-transferase kappa 1 Homo sapiens 32-36 23537991-1 2013 The glutathione S-transferases (GSTs) are a family of phase II xenobiotic metabolizing enzymes known to be involved in the detoxification and elimination of reactive oxygen species (ROS), thus defending tissues against oxidative stress. Reactive Oxygen Species 182-185 glutathione S-transferase kappa 1 Homo sapiens 32-36