PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24297047-8 2014 Angiostatin treatment, before or after LPS-induced neutrophil activation, inhibited phosphorylation of p38 and p44/42 MAPKs, abolished reactive oxygen species production and released the neutrophils from suppressed apoptosis, as indicated by expression of activated caspase-3 and morphological evidence of apoptosis. Reactive Oxygen Species 135-158 plasminogen Mus musculus 0-11 14651966-8 2003 These results suggest that plasminogen activates microglia via stimulation of ROS production. Reactive Oxygen Species 78-81 plasminogen Mus musculus 27-38 14651966-0 2003 Plasminogen-induced IL-1beta and TNF-alpha production in microglia is regulated by reactive oxygen species. Reactive Oxygen Species 83-106 plasminogen Mus musculus 0-11 14651966-6 2003 Reactive oxygen species (ROS) appeared to play an important role in plasminogen-induced microglial activation, with ROS being generated within 15min of plasminogen treatment, and antioxidants (100 microM trolox and 10mM NAC) reducing IL-1beta and TNF-alpha expression in plasminogen-treated cells. Reactive Oxygen Species 0-23 plasminogen Mus musculus 68-79 14651966-6 2003 Reactive oxygen species (ROS) appeared to play an important role in plasminogen-induced microglial activation, with ROS being generated within 15min of plasminogen treatment, and antioxidants (100 microM trolox and 10mM NAC) reducing IL-1beta and TNF-alpha expression in plasminogen-treated cells. Reactive Oxygen Species 0-23 plasminogen Mus musculus 152-163 14651966-6 2003 Reactive oxygen species (ROS) appeared to play an important role in plasminogen-induced microglial activation, with ROS being generated within 15min of plasminogen treatment, and antioxidants (100 microM trolox and 10mM NAC) reducing IL-1beta and TNF-alpha expression in plasminogen-treated cells. Reactive Oxygen Species 0-23 plasminogen Mus musculus 152-163 14651966-6 2003 Reactive oxygen species (ROS) appeared to play an important role in plasminogen-induced microglial activation, with ROS being generated within 15min of plasminogen treatment, and antioxidants (100 microM trolox and 10mM NAC) reducing IL-1beta and TNF-alpha expression in plasminogen-treated cells. Reactive Oxygen Species 25-28 plasminogen Mus musculus 68-79 14651966-6 2003 Reactive oxygen species (ROS) appeared to play an important role in plasminogen-induced microglial activation, with ROS being generated within 15min of plasminogen treatment, and antioxidants (100 microM trolox and 10mM NAC) reducing IL-1beta and TNF-alpha expression in plasminogen-treated cells. Reactive Oxygen Species 116-119 plasminogen Mus musculus 68-79