PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19321813-8 2009 Addition of an EPHX1 inhibitor, cyclohexene oxide (CHO) or 1,1,1-trichloropropene 2,3-oxide (TCPO), to the culture medium increased intracellular and extracellular ROS levels of OE-E6/E7 cells and suppressed the beneficial effect of the cells on embryo development; CHO and TCPO at these concentrations had no adverse effect on OE-E6/E7 growth and embryo development in vitro. Reactive Oxygen Species 164-167 epoxide hydrolase 1 Homo sapiens 15-20 26295053-2 2015 We hypothesized that glutathione S-transferase (GST M1, T1, and P1), reactive oxygen species (ROS) related metabolic genes (NQO1, EPHX1, and HO-1), and DNA repair genes (XRCC1, XPD, hOGG1, and ATM) together may play a role in arsenic-induced skin carcinogenesis. Reactive Oxygen Species 94-97 epoxide hydrolase 1 Homo sapiens 130-135 14726935-2 2004 The glutathione-S-transferases (GST) family and microsomal epoxide hydrolase (mEPHx) enzymes detoxify ROS, and genetic polymorphisms alter this detoxification. Reactive Oxygen Species 102-105 epoxide hydrolase 1 Homo sapiens 48-76