PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34481042-8 2021 However, incubation with GSH and purified glutathione S-transferase (GST) almost abolished ROS production by XO. Reactive Oxygen Species 91-94 hematopoietic prostaglandin D synthase Rattus norvegicus 42-67 34481042-8 2021 However, incubation with GSH and purified glutathione S-transferase (GST) almost abolished ROS production by XO. Reactive Oxygen Species 91-94 hematopoietic prostaglandin D synthase Rattus norvegicus 69-72 35421786-7 2022 Additionally, it reduced the enzymatic activities of catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GPx), glutathione reductase (GSR) and glutathione-S-transferase (GST), in addition to glutathione (GSH) content, whereas levels of malondialdehyde (MDA) and reactive oxygen species (ROS) were escalated. Reactive Oxygen Species 278-301 hematopoietic prostaglandin D synthase Rattus norvegicus 159-184 34481042-13 2021 Collectively, our findings demonstrate for the first time that cytoplasmic ROS sources, such as XOR, can also be inhibited by glutathionylation and these reactions are enzymatically mediated by GST. Reactive Oxygen Species 75-78 hematopoietic prostaglandin D synthase Rattus norvegicus 194-197 35421786-7 2022 Additionally, it reduced the enzymatic activities of catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GPx), glutathione reductase (GSR) and glutathione-S-transferase (GST), in addition to glutathione (GSH) content, whereas levels of malondialdehyde (MDA) and reactive oxygen species (ROS) were escalated. Reactive Oxygen Species 303-306 hematopoietic prostaglandin D synthase Rattus norvegicus 159-184 21933223-5 2012 Pb and Cd caused an increase in reactive oxygen species (ROS) by elevating testicular malondialdehydes (MDA) and decrease in activities of testicular antioxidant enzymes superoxide dismutase (SOD), catalase, glucose 6 phosphate dehydrogenase (G6PDH) and glutathione-S-transferase (GST) in mitochondrial and/or post-mitochondrial fraction. Reactive Oxygen Species 57-60 hematopoietic prostaglandin D synthase Rattus norvegicus 254-279 27852938-1 2017 Glutathione-S-transferase (GST) and cytochrome P450 family 1 subfamily A polypeptide 1 (CYP1A1) metabolize and detoxify carcinogens, drugs, environmental pollutants, and reactive oxygen species. Reactive Oxygen Species 170-193 hematopoietic prostaglandin D synthase Rattus norvegicus 0-25 27852938-1 2017 Glutathione-S-transferase (GST) and cytochrome P450 family 1 subfamily A polypeptide 1 (CYP1A1) metabolize and detoxify carcinogens, drugs, environmental pollutants, and reactive oxygen species. Reactive Oxygen Species 170-193 hematopoietic prostaglandin D synthase Rattus norvegicus 27-30 23111281-4 2013 Gene expression profiles of BB rat islets were highly distinct from F344 islets and under-expressed numerous genes involved in ROS metabolism, including glutathione S-transferase (GST) family members (Gstm2, Gstm4, Gstm7, Gstt1, Gstp1, and Gstk1), superoxide dismutases (Sod2 and Sod3), peroxidases, and peroxiredoxins. Reactive Oxygen Species 127-130 hematopoietic prostaglandin D synthase Rattus norvegicus 153-178 23111281-4 2013 Gene expression profiles of BB rat islets were highly distinct from F344 islets and under-expressed numerous genes involved in ROS metabolism, including glutathione S-transferase (GST) family members (Gstm2, Gstm4, Gstm7, Gstt1, Gstp1, and Gstk1), superoxide dismutases (Sod2 and Sod3), peroxidases, and peroxiredoxins. Reactive Oxygen Species 127-130 hematopoietic prostaglandin D synthase Rattus norvegicus 180-183 26987645-10 2016 Different antioxidant enzymes were also evaluated and revealed a notable decline in the level of glutathione and glutathione-S-transferase activity leading to the augmented generation of reactive oxygen species. Reactive Oxygen Species 187-210 hematopoietic prostaglandin D synthase Rattus norvegicus 113-138 21933223-5 2012 Pb and Cd caused an increase in reactive oxygen species (ROS) by elevating testicular malondialdehydes (MDA) and decrease in activities of testicular antioxidant enzymes superoxide dismutase (SOD), catalase, glucose 6 phosphate dehydrogenase (G6PDH) and glutathione-S-transferase (GST) in mitochondrial and/or post-mitochondrial fraction. Reactive Oxygen Species 57-60 hematopoietic prostaglandin D synthase Rattus norvegicus 281-284 21590696-11 2011 The data suggest that thyroid hormone changes determine ROS concentration changes and decrease of some antioxidant defences that would lead to a compensatory answer of the GST and GPx enzymes, which could be consider as credible biomarkers. Reactive Oxygen Species 56-59 hematopoietic prostaglandin D synthase Rattus norvegicus 172-175 1632648-1 1992 The mechanism of oxygen radical-dependent activation of hepatic microsomal glutathione S-transferase by hydrogen peroxide was studied. Reactive Oxygen Species 17-31 hematopoietic prostaglandin D synthase Rattus norvegicus 75-100 14726301-8 2004 The DOX-induced increase in ROS was reduced to control levels by maximal GST overexpression. Reactive Oxygen Species 28-31 hematopoietic prostaglandin D synthase Rattus norvegicus 73-76 14726301-9 2004 Coincident with this elimination of oxidative stress, there was a reduction in both Trypan blue and TUNEL-positive cells, indicating that GST overexpression reduced both ROS and cell death in this model system. Reactive Oxygen Species 170-173 hematopoietic prostaglandin D synthase Rattus norvegicus 138-141 9774493-14 1998 The inhibition in GST activity in tissues was observed probably due to increased ROS generation, however, GST activity partially recovered by 12 h after the second dose of ISO, in an attempt to counteract oxidative stress. Reactive Oxygen Species 81-84 hematopoietic prostaglandin D synthase Rattus norvegicus 18-21 19584028-2 2009 Adaptation to moderate H/R enhanced in mitochondria the production and activity of reactive oxygen species scavengers, such as glutathione, manganese superoxide dismutase, glutathione peroxidase, and glutathione-S-transferase. Reactive Oxygen Species 83-106 hematopoietic prostaglandin D synthase Rattus norvegicus 200-225 12215683-1 2002 The present studies were to test the hypotheses that glutathione reductase (GR), glutathione peroxidase (GPX), and glutathione S-transferase (GST) activities are expressed in nuclei and nucleoli of rat liver cells, and that differences in activities of these enzymes would correlate with the greater resistance of female than of male Fischer-344 rats to hepatic necrosis in vivo, mediated by reactive oxygen species generated by redox-cycling metabolism of diquat. Reactive Oxygen Species 392-415 hematopoietic prostaglandin D synthase Rattus norvegicus 142-145 12115560-0 2002 Promoting effects of monomethylarsonic acid, dimethylarsinic acid and trimethylarsine oxide on induction of rat liver preneoplastic glutathione S-transferase placental form positive foci: a possible reactive oxygen species mechanism. Reactive Oxygen Species 199-222 hematopoietic prostaglandin D synthase Rattus norvegicus 132-157