PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32584135-0 2020 Follicle Stimulating Hormone Inhibits the Expression of p53 Up-Regulated Modulator of Apoptosis Induced by Reactive Oxygen Species Through PI3K/Akt in Mouse Granulosa Cells. Reactive Oxygen Species 107-130 BCL2 binding component 3 Mus musculus 56-95 32584135-5 2020 Therefore, we examined whether FSH inhibits the expression of p53 up-regulated modulator of apoptosis (PUMA) induced by reactive oxygen species (ROS) through phosphoinositide 3-kinase (PI3K) / protein kinase B (AKT) in mouse GCs. Reactive Oxygen Species 120-143 BCL2 binding component 3 Mus musculus 62-101 32584135-5 2020 Therefore, we examined whether FSH inhibits the expression of p53 up-regulated modulator of apoptosis (PUMA) induced by reactive oxygen species (ROS) through phosphoinositide 3-kinase (PI3K) / protein kinase B (AKT) in mouse GCs. Reactive Oxygen Species 120-143 BCL2 binding component 3 Mus musculus 103-107 32584135-5 2020 Therefore, we examined whether FSH inhibits the expression of p53 up-regulated modulator of apoptosis (PUMA) induced by reactive oxygen species (ROS) through phosphoinositide 3-kinase (PI3K) / protein kinase B (AKT) in mouse GCs. Reactive Oxygen Species 145-148 BCL2 binding component 3 Mus musculus 62-101 32584135-5 2020 Therefore, we examined whether FSH inhibits the expression of p53 up-regulated modulator of apoptosis (PUMA) induced by reactive oxygen species (ROS) through phosphoinositide 3-kinase (PI3K) / protein kinase B (AKT) in mouse GCs. Reactive Oxygen Species 145-148 BCL2 binding component 3 Mus musculus 103-107 32584135-9 2020 Additionally, we also found that PI3K/AKT inhibitor LY294002 abolished the downregulation of PUMA mRNA by FSH in vitro, In conclusion, FSH inhibit the expression of PUMA induced by ROS through PI3K/AKT pathway in vivo and vitro. Reactive Oxygen Species 181-184 BCL2 binding component 3 Mus musculus 93-97 32584135-9 2020 Additionally, we also found that PI3K/AKT inhibitor LY294002 abolished the downregulation of PUMA mRNA by FSH in vitro, In conclusion, FSH inhibit the expression of PUMA induced by ROS through PI3K/AKT pathway in vivo and vitro. Reactive Oxygen Species 181-184 BCL2 binding component 3 Mus musculus 165-169 32450188-8 2020 Besides, suppression of Bbc3 decreased the reactive oxygen species (ROS) level and radio of PI-positive cells. Reactive Oxygen Species 43-66 BCL2 binding component 3 Mus musculus 24-28 32450188-8 2020 Besides, suppression of Bbc3 decreased the reactive oxygen species (ROS) level and radio of PI-positive cells. Reactive Oxygen Species 68-71 BCL2 binding component 3 Mus musculus 24-28