PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21515403-11 2012 However, the treatment with rexinoids raises triglycerides levels, suppresses the thyroid hormone axis, and induces hepatomegaly, which has complicated the development of these compounds as therapeutic agents for the treatment of type 2 diabetes and insulin resistance. rexinoids 28-37 insulin Homo sapiens 250-257