PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15100098-7 2004 To further establish that the stimulation of sodium transport induced by insulin is related to PIP(3) levels, we transfected A6 cells with human PTEN cDNA and observed a 30% decrease in the natriferic effect of insulin. Sodium 45-51 phosphatase and tensin homolog Homo sapiens 145-149 15100098-8 2004 Similarly, the increase in sodium transport observed by addition of permeant PIP(3) was also reduced by 30% in PTEN-overexpressing cells. Sodium 27-33 phosphatase and tensin homolog Homo sapiens 111-115 31807182-9 2019 Furthermore, PTEN-knockdown decreased the expression of specific thyroid proteins (thyroglobulin, TG; thyroid peroxidase, TPO; and sodium/iodide symporter, NIS) and inhibited the iodide uptake ability of thyroid cells by downregulating PAX8, suggesting that PTEN deficiency may impair the function of thyroid cells. Sodium 131-137 phosphatase and tensin homolog Homo sapiens 13-17 34868940-0 2021 Elevated Sodium Pump alpha3 Subunit Expression Promotes Colorectal Liver Metastasis via the p53-PTEN/IGFBP3-AKT-mTOR Axis. Sodium 9-15 phosphatase and tensin homolog Homo sapiens 96-100 34868940-8 2021 Conclusions: Elevated expression of the sodium pump alpha3 subunit promotes CRC liver metastasis via the PTEN/IGFBP3-mediated mTOR pathway, suggesting that sodium pump alpha3 could represent a critical prognostic marker and/or therapeutic target for this disease. Sodium 40-46 phosphatase and tensin homolog Homo sapiens 105-109 33308227-0 2020 Bone marrow mesenchymal stem cells derived miRNA-130b enhances epithelial sodium channel by targeting PTEN. Sodium 74-80 phosphatase and tensin homolog Homo sapiens 102-106 26872488-2 2016 Herein, we demonstrated in cultured cells and in vivo that increased levels of extracellular Pi activated the AKT/mammalian target of rapamycin complex 1 (mTORC1) pathway by suppressing membrane-bound phosphatase and tensin homolog (PTEN) levels in a manner requiring the sodium-dependent Pi transporter PiT-1. Sodium 272-278 phosphatase and tensin homolog Homo sapiens 233-237 24270425-5 2013 PTEN KO lenses exhibited a progressive age-related increase in intracellular hydrostatic pressure, along with, increased intracellular sodium concentrations, and reduced Na+/K+-ATPase activity. Sodium 135-141 phosphatase and tensin homolog Homo sapiens 0-4