PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24349144-6	2013	The inserted sequence included the META motif, which has previously been implicated in increased sodium tolerance of the Hal2 homologue from a related fungal species.	Sodium	97-103	3'(2'),5'-bisphosphate nucleotidase	Saccharomyces cerevisiae S288C	121-125	
16352596-3	2006	However, pAp accumulates and 5"-3" degradation decreases in the presence of ions known to inhibit Hal2p activity, such as sodium or lithium.	Sodium	122-128	3'(2'),5'-bisphosphate nucleotidase	Saccharomyces cerevisiae S288C	98-103	
16352596-4	2006	We have shown that yeast cells can better adapt to the presence of sodium than lithium because of their ability to reduce pAp accumulation by activating HAL2 expression in a Gcn4p-dependent response, a regulatory loop that is likely to be conserved in different yeast species.	Sodium	67-73	3'(2'),5'-bisphosphate nucleotidase	Saccharomyces cerevisiae S288C	153-157	
11454443-5	2001	The recent visualization at the atomic level of the inhibitory site of sodium in the known target Hal2 has helped identify the interactions determining Na(+) toxicity.	Sodium	71-77	3'(2'),5'-bisphosphate nucleotidase	Saccharomyces cerevisiae S288C	98-102	
10656801-0	2000	X-ray structure of yeast Hal2p, a major target of lithium and sodium toxicity, and identification of framework interactions determining cation sensitivity.	Sodium	62-68	3'(2'),5'-bisphosphate nucleotidase	Saccharomyces cerevisiae S288C	25-30	
10656801-1	2000	The product of the yeast HAL2 gene (Hal2p) is an in vivo target of sodium and lithium toxicity and its overexpression improves salt tolerance in yeast and plants.	Sodium	67-73	3'(2'),5'-bisphosphate nucleotidase	Saccharomyces cerevisiae S288C	25-29	
10656801-1	2000	The product of the yeast HAL2 gene (Hal2p) is an in vivo target of sodium and lithium toxicity and its overexpression improves salt tolerance in yeast and plants.	Sodium	67-73	3'(2'),5'-bisphosphate nucleotidase	Saccharomyces cerevisiae S288C	36-41	
8910555-10	1996	These results suggest that the cation sensitivity of the HAL2 nucleotidase is an important determinant of the inhibition of yeast growth by sodium and lithium salts.	Sodium	140-146	3'(2'),5'-bisphosphate nucleotidase	Saccharomyces cerevisiae S288C	57-61