PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14999052-7 2004 In contrast, Hcrt/Orx responses were strongly attenuated by lowering extracellular Ca(2+) ( approximately 20 microM) but were not inhibited by concentrations of KB-R7943 (10 microM) selective for blockade of sodium/calcium exchange. Sodium 208-214 hypocretin Mus musculus 13-17 12388591-11 2002 Instead, in many cases the orexin A-induced current reversed in calcium-free medium at a value (-23 mV) consistent with the activation of a mixed cation channel (with relative permeabilities for sodium and potassium of 0.43 and 1, respectively). Sodium 195-201 hypocretin Mus musculus 27-35 12832517-5 2003 Acting on postsynaptic orexin type 2 receptors, orexin activates a sodium-calcium exchange current, thereby depolarizing the cell and increasing its firing frequency. Sodium 67-73 hypocretin Mus musculus 23-29 12832517-5 2003 Acting on postsynaptic orexin type 2 receptors, orexin activates a sodium-calcium exchange current, thereby depolarizing the cell and increasing its firing frequency. Sodium 67-73 hypocretin Mus musculus 48-54