PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24555036-4	2013	METHODS: In this short study, we (1) compared the biophysical properties of the sodium current (I Na) generated by the mouse Na v1.5 (mNa v1.5) and human Na v1.5 (hNa v1.5) constructs that were expressed in HEK293 cells, and (2) investigated the possible alterations of the biophysical properties of the human Na v1.5 construct that was modified with specific epitopes.	Sodium	80-86	immunoglobulin lambda variable 2-18	Homo sapiens	128-132	
26595809-1	2016	Increased sodium influx via incomplete inactivation of the major cardiac sodium channel Na(V)1.5 is correlated with an increased incidence of atrial fibrillation (AF) in humans.	Sodium	10-16	immunoglobulin lambda variable 2-18	Homo sapiens	88-96	
24555036-4	2013	METHODS: In this short study, we (1) compared the biophysical properties of the sodium current (I Na) generated by the mouse Na v1.5 (mNa v1.5) and human Na v1.5 (hNa v1.5) constructs that were expressed in HEK293 cells, and (2) investigated the possible alterations of the biophysical properties of the human Na v1.5 construct that was modified with specific epitopes.	Sodium	80-86	immunoglobulin lambda variable 2-18	Homo sapiens	138-142	
20618077-1	2010	The sodium channel isoform Na(v)1.5 mediates sodium current, excitability, and electrical conduction in the human heart.	Sodium	4-10	immunoglobulin lambda variable 2-18	Homo sapiens	27-35	
22052157-4	2012	Specifically, we compute the fast Fourier transform for a family of current traces at different step potentials for the inward rectifying potassium channel, K(ir)2.1, and the channel encoding the cardiac fast sodium current, Na(v)1.5.	Sodium	209-215	immunoglobulin lambda variable 2-18	Homo sapiens	225-233	
20167245-3	2011	Highly metastatic breast cancer cells express Na(V)1.5, the main isoform expressed in cardiac cells, where the current generated by the flux of sodium ions is responsible for the excitability.	Sodium	144-150	immunoglobulin lambda variable 2-18	Homo sapiens	46-54	
21840964-6	2011	Importantly, we also expressed the peptide spanning the H558R polymorphism with 8 additional BrS Na(v)1.5 mutations with reduced currents and demonstrated that the peptide was able to restore significant sodium currents in 4 of them.	Sodium	204-210	immunoglobulin lambda variable 2-18	Homo sapiens	97-105	
19176528-2	2009	MDA-MB-231 breast cancer cells express functional sodium channel complexes, consisting of Na(V)1.5 and associated auxiliary beta-subunits, that are responsible for a sustained inward sodium current at the membrane potential.	Sodium	50-56	immunoglobulin lambda variable 2-18	Homo sapiens	90-98	
20558140-6	2010	Mutation A130V dramatically decreased the cardiac sodium current density when expressed in HEK293/Na(v)1.5 stable cell line, but did not have significant effect on kinetics of activation, inactivation, and channel recovery from inactivation.	Sodium	50-56	immunoglobulin lambda variable 2-18	Homo sapiens	98-106	
19632629-12	2009	Unexpectedly, the 94-amino-acid fusion peptide derived from the R34fs/60 mutation accentuated the late sodium current of R1195H-containing Na(V)1.5 channels in vitro.	Sodium	103-109	immunoglobulin lambda variable 2-18	Homo sapiens	139-147	
19077543-2	2008	Ranolazine, an anti-ischemic drug, has been shown to block cardiac (Na(V)1.5) late sodium current (I(Na)).	Sodium	83-89	immunoglobulin lambda variable 2-18	Homo sapiens	68-76	
17935523-1	2007	AIM: Sodium current (I(Na)) of the mammalian heart is resistant to tetrodotoxin (TTX) due to low TTX affinity of the cardiac sodium channel (Na(v)) isoform Na(v)1.5.	Sodium	5-11	immunoglobulin lambda variable 2-18	Homo sapiens	156-164	
19133985-10	2009	CONCLUSIONS AND IMPLICATIONS: F 15845 is a selective, potent blocker of the persistent sodium current, generated by the human Na(v)1.5 channel isoforms, and prevents cardiac angina in animal models.	Sodium	87-93	immunoglobulin lambda variable 2-18	Homo sapiens	126-134	
17060380-11	2006	Electrophysiological analysis of sodium current in HEK293 cells stably expressing hNa(v)1.5 and transiently transfected with wild-type and mutant caveolin-3 demonstrated that mutant caveolin-3 results in a 2- to 3-fold increase in late sodium current compared with wild-type caveolin-3.	Sodium	33-39	immunoglobulin lambda variable 2-18	Homo sapiens	82-91	
15831816-3	2005	Sodium currents were acquired by whole cell recording on HEK-293 cells transiently expressing Na(V)1.5.	Sodium	0-6	immunoglobulin lambda variable 2-18	Homo sapiens	94-102