PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30033800-0	2019	Schisanhenol improves learning and memory in scopolamine-treated mice by reducing acetylcholinesterase activity and attenuating oxidative damage through SIRT1-PGC-1alpha-Tau signaling pathway.	schisanhenol	0-12	sirtuin 1	Mus musculus	153-158	
30033800-9	2019	Furthermore, western blotting analysis revealed that Schisanhenol increased the levels of SIRT1 and PGC-1alpha and decreased the level of phosphorylated Tau protein (Ser 396) significantly in the hippocampal tissues.	schisanhenol	53-65	sirtuin 1	Mus musculus	90-95	
30033800-10	2019	CONCLUSIONS: Our findings indicated that Schisanhenol can attenuate scopolamine-induced learning impairment and enhance cognitive function, the mechanism via improve the cholinergic system and antioxidant ability, activate SIRT1-PGC1alpha signaling, inhibit the phosphorylation of Tau, and would be an effective candidate against cognitive disorders, such as Alzheimer"s disease.	schisanhenol	41-53	sirtuin 1	Mus musculus	223-228