PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22940226-5	2012	At transcriptional level of inflammatory cytokine genes, guggulipid and nimesulide down regulated MPTP-induced tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta) mRNA expressions with up regulations in interleukin-6 (IL-6) and interleukin-1alpha (IL-1alpha) mRNA expressions.	guggulu extract	57-67	interleukin 1 beta	Rattus norvegicus	155-172	
22940226-5	2012	At transcriptional level of inflammatory cytokine genes, guggulipid and nimesulide down regulated MPTP-induced tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta) mRNA expressions with up regulations in interleukin-6 (IL-6) and interleukin-1alpha (IL-1alpha) mRNA expressions.	guggulu extract	57-67	interleukin 1 beta	Rattus norvegicus	174-182	
31465983-7	2019	RESULTS: GL significantly inhibited the IL-1beta stimulated cartilage degradation in vitro by mitigating the MMPs activity, collagen degradation and secretion of pro-inflammatory mediators.	guggulu extract	9-11	interleukin 1 beta	Rattus norvegicus	40-48