PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9270872-0	1997	Echistatin induces decrease of pp125FAK phosphorylation, disassembly of actin cytoskeleton and focal adhesions, and detachment of fibronectin-adherent melanoma cells.	echistatin	0-10	fibronectin 1	Mus musculus	130-141	
21528271-1	1997	Echistatin, a low molecular weight, RGD-containing protein isolated from the venom of Echis carinatus, inhibited Lewis lung carcinoma cell (3LL) adhesion to immobilized fibronectin and laminin.	echistatin	0-10	fibronectin 1	Mus musculus	169-180	
21528271-3	1997	Echistatin showed a stronger activity in inhibiting cell adhesion to fibronectin rather than to laminin and it resulted about 3-fold more effective than kistrin, an other ROD-snake venom protein, in inhibiting 3LL cell attachment to both substrates.	echistatin	0-10	fibronectin 1	Mus musculus	69-80	
10931187-0	2000	Echistatin inhibits pp125FAK autophosphorylation, paxillin phosphorylation and pp125FAK-paxillin interaction in fibronectin-adherent melanoma cells.	echistatin	0-10	fibronectin 1	Mus musculus	112-123	
10931187-2	2000	The aim of this study was to establish the sequence of events downstream pp125FAK dephosphorylation that could be responsible for echistatin-induced disassembly of actin cytoskeleton and focal adhesions in fibronectin-adherent B16-BL6 melanoma cells.	echistatin	130-140	fibronectin 1	Mus musculus	206-217	
9270872-1	1997	B16-BL6 mouse melanoma cells cultured on fibronectin-coated dishes were detached by treatment with echistatin, an RGD-containing disintegrin.	echistatin	99-109	fibronectin 1	Mus musculus	41-52	
9270872-6	1997	Echistatin treatment down-regulated the phosphorylation of pp125FAK in fibronectin-adherent cells in a dose- and time-dependent fashion.	echistatin	0-10	fibronectin 1	Mus musculus	71-82	
15276326-6	2004	Either cell detachment or apoptotic response induced by echistatin were more pronounced on fibronectin-adherent GD25 cells than on vitronectin-adherent ones.	echistatin	56-66	fibronectin 1	Mus musculus	91-102	
7735124-5	1995	Native echistatin was also able to inhibit B16-BL6 cell attachment to IgG antihuman fibronectin receptor-coated wells, thus suggesting that the molecule binds to adhesive receptors on melanoma cell surface.	echistatin	7-17	fibronectin 1	Mus musculus	84-95