PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31541893-0	2019	The correlation between the methylation of PTEN gene and the apoptosis of osteosarcoma cells mediated by SeHA nanoparticles.	Selenious Acid	105-109	phosphatase and tensin homolog	Homo sapiens	43-47	
31541893-6	2019	Bisulfite Sequence PCR of PTEN gene exhibited about (22.40 +- 5.39)%, (45.91 +- 6.36)% and (25.90 +- 5.36)% promoter methylation in control, HA and SeHA group.	Selenious Acid	148-152	phosphatase and tensin homolog	Homo sapiens	26-30	
31541893-12	2019	Compared the methylation status of PTEN gene in each group, it was confirming that SeHA nanoparticles hardly possessed the de-methylation effect, but the pure HA strikingly increased the methylation level of such gene.	Selenious Acid	83-87	phosphatase and tensin homolog	Homo sapiens	35-39	
31541893-13	2019	It seemed the dopant selenite ions possessed de-methylation effect onto PTEN gene.	Selenious Acid	21-29	phosphatase and tensin homolog	Homo sapiens	72-76	
23392169-0	2013	PTEN-regulated AKT/FoxO3a/Bim signaling contributes to reactive oxygen species-mediated apoptosis in selenite-treated colorectal cancer cells.	Selenious Acid	101-109	phosphatase and tensin homolog	Homo sapiens	0-4	
27902968-5	2017	Mechanistically, selenite promotes association of APC/C-CDH1 with GLS1 and leads to GLS1 degradation by ubiquitination, this process is related to induction of PTEN expression.	Selenious Acid	17-25	phosphatase and tensin homolog	Homo sapiens	160-164	
23392169-4	2013	First, we found that selenite treatment in HCT116 and SW480 CRC cells caused inhibition of AKT and the nuclear accumulation of FoxO3a by western blot and immunofluorescence analyses, respectively, thereby facilitating transcription of the target genes bim and PTEN.	Selenious Acid	21-29	phosphatase and tensin homolog	Homo sapiens	260-264	
23392169-8	2013	In summary, our results show that selenite could induce ROS-dependent FoxO3a-mediated apoptosis in CRC cells and xenograft tumors through PTEN-mediated inhibition of the PI3K/AKT survival axis.	Selenious Acid	34-42	phosphatase and tensin homolog	Homo sapiens	138-142	
19373605-4	2009	The treatment of DU-145 cells with increasing concentrations of Se induced an increase in PTEN lipid phosphatase activity by twofold, which correlated with a decrease in phospho-ser(473)-Akt, and an increase in phospho-Ser(370)-PTEN levels.	Selenious Acid	64-66	phosphatase and tensin homolog	Homo sapiens	90-94	
19373605-4	2009	The treatment of DU-145 cells with increasing concentrations of Se induced an increase in PTEN lipid phosphatase activity by twofold, which correlated with a decrease in phospho-ser(473)-Akt, and an increase in phospho-Ser(370)-PTEN levels.	Selenious Acid	64-66	phosphatase and tensin homolog	Homo sapiens	228-232