PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27183385-2 2016 CBS condenses homocysteine and serine to cystathionine that is then converted to cysteine. Cystathionine 41-54 cystathionine beta-synthase Mus musculus 0-3 15105297-2 2004 Cystathionine beta-synthase (CBS) is an enzyme that condenses homocysteine with serine to form cystathionine. Cystathionine 95-108 cystathionine beta-synthase Mus musculus 0-27 15105297-2 2004 Cystathionine beta-synthase (CBS) is an enzyme that condenses homocysteine with serine to form cystathionine. Cystathionine 95-108 cystathionine beta-synthase Mus musculus 29-32 33949005-1 2021 Cystathionine beta-synthase (CBS) is a key enzyme of the trans-sulfuration pathway that converts homocysteine to cystathionine. Cystathionine 113-126 cystathionine beta-synthase Mus musculus 0-27 33949005-1 2021 Cystathionine beta-synthase (CBS) is a key enzyme of the trans-sulfuration pathway that converts homocysteine to cystathionine. Cystathionine 113-126 cystathionine beta-synthase Mus musculus 29-32 29803556-1 2018 Cystathionine-beta-synthase (CBS) gene encodes L-serine hydrolyase which catalyzes beta-reaction to condense serine with homocysteine (Hcy) by pyridoxal-5"-phosphate helps to form cystathionine which in turn is converted to cysteine. Cystathionine 180-193 cystathionine beta-synthase Mus musculus 0-27 29803556-1 2018 Cystathionine-beta-synthase (CBS) gene encodes L-serine hydrolyase which catalyzes beta-reaction to condense serine with homocysteine (Hcy) by pyridoxal-5"-phosphate helps to form cystathionine which in turn is converted to cysteine. Cystathionine 180-193 cystathionine beta-synthase Mus musculus 29-32 28821635-1 2017 Classical homocystinuria (HCU) is an inborn error of sulfur amino acid metabolism caused by deficient activity of cystathionine beta-synthase (CBS), resulting in an accumulation of homocysteine and a concomitant decrease of cystathionine and cysteine in blood and tissues. Cystathionine 114-127 cystathionine beta-synthase Mus musculus 143-146 23315129-1 2013 Cystathionine-beta-synthase (CBS) catalyzes the condensation of serine with homocysteine to form cystathionine and occupies a crucial regulatory position between the methionine cycle and the biosynthesis of cysteine by transsulfuration. Cystathionine 97-110 cystathionine beta-synthase Mus musculus 0-27 23350603-4 2013 Accumulation of cystathionine and lanthionine appeared to result from cystathionine beta-synthase (CBS)-mediated cysteine desulfhydration. Cystathionine 16-29 cystathionine beta-synthase Mus musculus 70-97 23315129-1 2013 Cystathionine-beta-synthase (CBS) catalyzes the condensation of serine with homocysteine to form cystathionine and occupies a crucial regulatory position between the methionine cycle and the biosynthesis of cysteine by transsulfuration. Cystathionine 97-110 cystathionine beta-synthase Mus musculus 29-32 22854956-2 2012 In mammals, cystathionine is formed as an intermediate of the transsulfuration pathway by the condensation of serine and homocysteine (Hcy) in a reaction catalyzed by cystathionine beta-synthase (CBS). Cystathionine 12-25 cystathionine beta-synthase Mus musculus 167-194 23470016-1 2013 UNLABELLED: Abstract Purpose: Cystathionine beta-synthase (CBS), a key enzyme in the transsulfuration metabolic pathway, converts homocysteine to cystathionine, which is converted to cysteine required for the synthesis of major retinal antioxidant glutathione (GSH). Cystathionine 146-159 cystathionine beta-synthase Mus musculus 30-57 23470016-1 2013 UNLABELLED: Abstract Purpose: Cystathionine beta-synthase (CBS), a key enzyme in the transsulfuration metabolic pathway, converts homocysteine to cystathionine, which is converted to cysteine required for the synthesis of major retinal antioxidant glutathione (GSH). Cystathionine 146-159 cystathionine beta-synthase Mus musculus 59-62 22854956-2 2012 In mammals, cystathionine is formed as an intermediate of the transsulfuration pathway by the condensation of serine and homocysteine (Hcy) in a reaction catalyzed by cystathionine beta-synthase (CBS). Cystathionine 12-25 cystathionine beta-synthase Mus musculus 196-199 21898591-4 2011 CBS converts HCY to cystathionine, thereby committing it to cysteine synthesis. Cystathionine 20-33 cystathionine beta-synthase Mus musculus 0-3 17537983-5 2007 The higher renal CBS activity in males (22.7 +/- 3.1 mmol cystathionine.h(-1).kg kidney(-1)) vs. females (8.4 +/- 3.4 mmol cystathionine.h(-1).kg kidney(-1), P < or = 10(-6)) in C57Bl/6J mice was associated with lower plasma tHcy levels in males vs. females, and this difference was exacerbated in Cbs+/- mice (7.7 +/- 1.9 micromol/l in males vs. 13.8 +/- 6.4 micromol/l in females, P = 0.005). Cystathionine 58-71 cystathionine beta-synthase Mus musculus 17-20 17537983-5 2007 The higher renal CBS activity in males (22.7 +/- 3.1 mmol cystathionine.h(-1).kg kidney(-1)) vs. females (8.4 +/- 3.4 mmol cystathionine.h(-1).kg kidney(-1), P < or = 10(-6)) in C57Bl/6J mice was associated with lower plasma tHcy levels in males vs. females, and this difference was exacerbated in Cbs+/- mice (7.7 +/- 1.9 micromol/l in males vs. 13.8 +/- 6.4 micromol/l in females, P = 0.005). Cystathionine 123-136 cystathionine beta-synthase Mus musculus 17-20 20638879-1 2010 Cystathionine beta-synthase (CBS) catalyzes the condensation of homocysteine (Hcy) and serine to cystathionine, which is then hydrolyzed to cysteine by cystathionine gamma-lyase. Cystathionine 97-110 cystathionine beta-synthase Mus musculus 0-27 20638879-1 2010 Cystathionine beta-synthase (CBS) catalyzes the condensation of homocysteine (Hcy) and serine to cystathionine, which is then hydrolyzed to cysteine by cystathionine gamma-lyase. Cystathionine 97-110 cystathionine beta-synthase Mus musculus 29-32 17663144-1 2007 CBS is a vitamin B6-dependent transsulfuration enzyme needed to synthesize cysteine from methionine, catalyzing the condensation of serine with homocysteine to form cystathionine. Cystathionine 165-178 cystathionine beta-synthase Mus musculus 0-3 17461778-7 2007 The conversion of homocysteine into cystathionine, a rate-limiting step in trans-sulfuration catalysed by cystathionine beta-synthase, was comparatively less efficient in the old mice, as indicated by cystathionine/homocysteine ratios. Cystathionine 36-49 cystathionine beta-synthase Mus musculus 106-133