PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12056889-6	2002	NMR studies with these six single-site mutants reveal significant interactions of Lys 11 and Lys 29 with Glu 34 and Asp 21, respectively: pK(a) values for Glu 34 and Asp 21 increase by approximately 0.5-0.8 pH unit, similar to predicted values, when the lysines are replaced by neutral residues.	Lysine	254-261	beta-secretase 2	Homo sapiens	116-122	
20045648-5	2010	We have taken advantage of the amino acid difference between the BACE1 and BACE2 at the S2" pocket (BACE1 Pro(70) changed to BACE2 Lys(86)) to build ligands with >500-fold selectivity against BACE2.	Lysine	131-134	beta-secretase 2	Homo sapiens	75-80	
20045648-5	2010	We have taken advantage of the amino acid difference between the BACE1 and BACE2 at the S2" pocket (BACE1 Pro(70) changed to BACE2 Lys(86)) to build ligands with >500-fold selectivity against BACE2.	Lysine	131-134	beta-secretase 2	Homo sapiens	125-130	
20045648-5	2010	We have taken advantage of the amino acid difference between the BACE1 and BACE2 at the S2" pocket (BACE1 Pro(70) changed to BACE2 Lys(86)) to build ligands with >500-fold selectivity against BACE2.	Lysine	131-134	beta-secretase 2	Homo sapiens	125-130	
12056889-6	2002	NMR studies with these six single-site mutants reveal significant interactions of Lys 11 and Lys 29 with Glu 34 and Asp 21, respectively: pK(a) values for Glu 34 and Asp 21 increase by approximately 0.5-0.8 pH unit, similar to predicted values, when the lysines are replaced by neutral residues.	Lysine	254-261	beta-secretase 2	Homo sapiens	166-172	
1896431-5	1991	The significance of some changes in the catalytic site is uncertain due to the intrusion of a symmetry related Lys-70 side chain which hydrogen bonds to both Asp-21 and Glu-43.	Lysine	111-114	beta-secretase 2	Homo sapiens	158-164	
9876119-7	1999	Positively charged surface regions of aldolase (residues Lys 13, 27, 288, 293, and 341 and Arg 257) are attracted to the negatively charged amino terminus (Asp 1 and Glu 2 and 4) and other patches (Asp 24, 25, and 363 and Glu 361, 364, 99, and 100) of actin subunits.	Lysine	57-60	beta-secretase 2	Homo sapiens	156-161