PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22383527-8 2012 In MDA-MB-435 cells that demonstrate high active levels of the Rac GEF Vav2, EHop-016 inhibits the association of Vav2 with a nucleotide-free Rac1(G15A), which has a high affinity for activated GEFs. N4-(9-ethyl-9H-carbazol-3-yl)-N2-(3-morpholin-4-ylpropyl)-pyrimidine-2,4-diamine 77-85 vav guanine nucleotide exchange factor 2 Homo sapiens 71-75 22383527-8 2012 In MDA-MB-435 cells that demonstrate high active levels of the Rac GEF Vav2, EHop-016 inhibits the association of Vav2 with a nucleotide-free Rac1(G15A), which has a high affinity for activated GEFs. N4-(9-ethyl-9H-carbazol-3-yl)-N2-(3-morpholin-4-ylpropyl)-pyrimidine-2,4-diamine 77-85 vav guanine nucleotide exchange factor 2 Homo sapiens 114-118