PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
14741443-5	2004	Furthermore, THC administration resulted in decreased levels of mRNA for the pro-inflammatory cytokines interleukin-1 alpha, interleukin-1 beta, and tumor necrosis factor alpha for neonatal rat microglia co-cultured with Acanthamoeba.	Dronabinol	13-16	tumor necrosis factor	Rattus norvegicus	149-176	
27422357-8	2016	Moreover, in the same brain region, adolescent THC treatment also resulted in a persistent neuroinflammatory state, characterized by increased expression of the astrocyte marker, GFAP, increased levels of the pro-inflammatory markers, TNF-alpha, iNOS and COX-2, as well as a concomitant reduction of the anti-inflammatory cytokine, IL-10.	Dronabinol	47-50	tumor necrosis factor	Rattus norvegicus	235-244	
22189757-6	2012	We also showed that THC induced macrophage infiltration and increased expression of the inflammatory cytokine tumor necrosis factor alpha (TNF-alpha) in adipose tissue but did not induce apoptosis as measured by TUNEL staining.	Dronabinol	20-23	tumor necrosis factor	Rattus norvegicus	139-148	
22189757-6	2012	We also showed that THC induced macrophage infiltration and increased expression of the inflammatory cytokine tumor necrosis factor alpha (TNF-alpha) in adipose tissue but did not induce apoptosis as measured by TUNEL staining.	Dronabinol	20-23	tumor necrosis factor	Rattus norvegicus	110-137	
10594923-2	2000	Exposure of neonatal rat cortical microglial cells to the exogenous cannabinoid delta(9)-tetrahydrocannabinol (THC) resulted in reduced amounts of lipopolysaccharide (LPS)-induced mRNAs for IL-1alpha, IL-1beta, IL-6, and TNF-alpha.	Dronabinol	80-109	tumor necrosis factor	Rattus norvegicus	221-230	
10594923-2	2000	Exposure of neonatal rat cortical microglial cells to the exogenous cannabinoid delta(9)-tetrahydrocannabinol (THC) resulted in reduced amounts of lipopolysaccharide (LPS)-induced mRNAs for IL-1alpha, IL-1beta, IL-6, and TNF-alpha.	Dronabinol	111-114	tumor necrosis factor	Rattus norvegicus	221-230	
31081965-9	2019	Furthermore, mRNA expression of Kruppel-like factor-4, secreted immunopositive cell number changes of interleukin-6, nuclear factor kappabeta (NF-kappabeta), and peroxisome proliferator-activated receptor-gamma and tumor necrosis factor alpha (TNF-alpha) levels were analyzed for the immunomodulatory activity of THC.	Dronabinol	313-316	tumor necrosis factor	Rattus norvegicus	215-242	
31081965-9	2019	Furthermore, mRNA expression of Kruppel-like factor-4, secreted immunopositive cell number changes of interleukin-6, nuclear factor kappabeta (NF-kappabeta), and peroxisome proliferator-activated receptor-gamma and tumor necrosis factor alpha (TNF-alpha) levels were analyzed for the immunomodulatory activity of THC.	Dronabinol	313-316	tumor necrosis factor	Rattus norvegicus	244-253	
26499171-6	2015	Present data indicate that adolescent THC administration induces a persistent neuroinflammatory state specifically localized within the adult prefrontal cortex (PFC), characterized by increased expression of the pro-inflammatory markers, TNF-alpha, iNOS and COX-2, and reduction of the anti-inflammatory cytokine, IL-10.	Dronabinol	38-41	tumor necrosis factor	Rattus norvegicus	238-247